Vitamin A Acid / Tretinoin / Retinoic Acid 302-79-4

Retinoic acid (is also called Vitamin A acid / Tretinoin /) is a metabolite of vitamin A and plays an important role in cell growth, differentiation and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptor α/β/γ The IC50 is 14 nm. Retinoic acid and PPAR β/δ  The combined Kd value is 17 nm. Retinoic acid can inhibit transcription factor Nrf2 by activating retinoic acid receptor.

Function of Retinoic Acid
1. Retinoic acid is the acid form of vitamin a and so also known as all-trans retinoic acid or atra.

2. Retinoic acid is a drug commonly used to treat acne vulgaris and keratosis pilaris.

3. Retinoic acid is available as a cream or gel.retinoic acid is also used to treat acute promyelocytic leukemia.

4. Retinoic acid can stimulate skin growth and keep epidermic normal.

5. Retinoic acid can slow down skin aging process for solarization, remove tiny wrinkles, and retinoic acid canreduce skin roughness, so skin will become ruddy.