VERDOT Ips² InPlace™ Process-scale Chromatography Column

VERDOT Ips² InPlace process-scale chromatography columns are designed for industrial applications and allow contained filling,  packing,  unpacking,  and cleaning in place. The columns have a sanitary design, variable height adaptor, inflatable seal, and special low-shear valves for safe slurry transfer.

VERDOT Ips² InPlace columns have been designed so that the packing, unpacking, and cleaning-in-place features do not interfere with the bed support, distribution system, and column tube,  thus allowing optimum performance during any operation.

These columns are directly scalable and retain the same general design from pilot to manufacturing scale.  For instance, slurry valves can be added or removed to correlate with column diameter so that the efficiency of packing and unpacking in place is kept across the entire range of dimensions.

Column packing, unpacking and cleaning can be fully automated with the optional advanced control console or packing station.

VERDOT Ips² InPlace columns are available in many standard sizes and columns can be built in any tube height up to 1,400 mm or any diameter up to 2 m. The scale and scope of a project will seldom pose a constraint.

VERDOT Ips²  InPlace columns are available with glass, stainless steel, or acrylic column tubes.

• Cleaning in place of all wetted surfaces before column packing or unpacking

• Even distribution of the slurry over the column diameter during transfer

• Complete slurry transfer in syringe  mode using the motorized adaptor

• Self degassing before packing

• Reslurrying & unpacking in place with less than 2.5CV of buffer

• Cleaning in place of the column

• Maintenance in  place using the Column Lifter or optional Maintenance in place

• Closed system design

• Ideal for all media

• Variable height adaptor for  axial compression

• Supports multiple packing methods

• Fullly automated packing, unpacking & cleaning (optional)

• Reliable, sanitary and fast hydropneumatic   inflatable sealing system

• Low mechanical shear during media transfer

• Hoist-free operation   with optional Column Lifter or Maintenance in Place

• Complete: documentation for regulatory submissions

• Customizable: diameter up to 2.2m

For more information please visit Bio-Link website.