Urolithin B Powder

What Are The Benefits? 

1.Recently, researchers evaluated the function of urolithin B (UB) in HCC. Researchers investigated the effect of UB on cell survival, cell cycle and apoptosis in HCC cells, and found that UB can inhibit the proliferation of HCC cells by causing cell cycle arrest and apoptosis. More importantly, UB was able to increase the expression of phosphorylated β-catenin and block its translocation from the total nucleus to the cytoplasm. Thereby inducing deactivation of Wnt/β-catenin signaling.

2.Based on these findings, UB can attenuate the progression of osteoporosis in ovx mice, and we consider UB to be a potentially safe and effective treatment option for osteoporosis. In some examples of in vitro studies, ub can inhibit osteoclast activation by inhibiting the erk/nfκb signaling pathway. ub significantly inhibited the formation of bone resorption pits mediated by osteoclasts in a concentration-dependent manner, indicating that ub could inhibit the bone resorption function of osteoclasts in vitro.

3.Urolithin (Uro) B is a natural compound produced by gut bacteria from ingested ellagitannins (ET) and ellagic acid (EA), complex polyphenols found in pomegranate, raspberry, In foods such as blueberries and chestnuts. Uro B has recently attracted considerable attention due to its broad nutraceutical benefits and relatively high potency. According to several studies, Uro B has powerful antioxidant and anti-inflammatory properties that may prevent hyperlipidemia, the development of cardiovascular disease (CVD).

4.The well-known beneficial effect of Uro B in preclinical models is the attenuation of detrimental inflammatory responses, which can be clinically relevant in the cases of most chronic immune diseases. This chronic phenomenon is called “inflamm-aging,” and contributes to a series of defects in immunological activity, including dysfunction and injury of immune cells and tissues .

5.Oxidative stress (OS) is caused by an imbalance between the excessive production of ROS and a biological system’s ability to readily detoxify ROS . Such imbalances damage multiple cellular processes, such as protein modification (oxidation, carbonylation), physiologically transporting signals via a second messenger or deoxyribose nucleic acid (DNA) replication and transcription . Increased ROS levels are implicated in many chronic metabolic diseases, e.g., diabetes, chronic kidney disease and neurodegenerative diseases. Some natural metabolites, such as those with good antioxidant activity, have become a hotspot of current research. Based on substantial evidence, Uro B possesses excellent antioxidant properties.

Application Direction

Urolithin B powder has very powerful anti-oxidation and anti-aging effects. As a raw material, it has been widely used in the fields of medicine and health care products. Its efficacy is still being explored, and its application will be more extensive in the future

Company Introduction And Certificates Obtained

Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

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