Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Block 14, No.100, Luyun Road, Changsha 410205, Hunan, China.

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Sample Provided: no

    Payment Terms: L/C

    Troxerutin is a bioflavonoid derivative that is commonly used in pharmaceuticals and nutraceuticals due to its potential health benefits, particularly in managing venous disorders. It's typically available in different forms, including powders, tablets, capsules, or creams. As of my last update in January 2022, Troxerutin in powder form is used as an active pharmaceutical ingredient (API) for various medicinal products, especially those targeting circulatory system-related conditions.

    Here is a general product description for Troxerutin powder as an API:

    Product Name: Troxerutin Powder Chemical Formula: C33H42O19 Molecular Weight: Approximately 742.68 g/mol Category: Flavonoid derivative, often classified as a bioflavonoid Source: Troxerutin is a naturally occurring flavonoid found in certain plants, including the Japanese pagoda tree (Sophora japonica).

    Mechanism of Action: Troxerutin is known for its venotonic and vasoprotective properties. It strengthens blood vessels, reduces capillary permeability, and exhibits antioxidant effects. Troxerutin primarily acts by improving blood flow, reducing inflammation, and protecting blood vessels, which can be beneficial in conditions like chronic venous insufficiency, hemorrhoids, and other venous disorders.

    Indications: Troxerutin is often used in the formulation of medications or supplements targeting venous disorders, such as chronic venous insufficiency, varicose veins, venous ulcers, and hemorrhoids.

    Dosage Form: Troxerutin powder is an active ingredient used in the manufacturing of various pharmaceutical dosage forms, including tablets, capsules, topical creams, and gels.

    Usage: The dosage and administration of Troxerutin depend on the specific formulation and the patient's condition. Dosages may vary according to the severity of the condition and the product's specific instructions provided by healthcare professionals.

    Side Effects: Troxerutin is generally considered safe when used as directed. However, some individuals may experience mild side effects such as gastrointestinal disturbances or allergic reactions. It's essential to consult a healthcare professional for guidance before using products containing Troxerutin, especially if you have any underlying health conditions or are taking other medications.

    Availability: Troxerutin powder as an API is primarily available to pharmaceutical manufacturers and compounding pharmacies for the production of medications and supplements targeting venous disorders.

     

    Inspection Item

     

    standard

     

    Inspection consequence

     

    conclusion

     

    Characteristics

     

    yellowsh-green crystalline powder hygroscopic.

     

    Yellowsh crystalline powder,

    hygroscopic.

     

     

    Conforms to regulation

     

     

     

    Identification

    A Infrared absorption CRS

    BResults the principal peak in the

    chromatogram obtained with the test

    solution is similar in position and size to

    the principal peak in the chromatogram

    obtained with the   reference

    solution(a)

     

    B Results the principal peak in the

    chromatogram obtained with the test

    solution is similar in position and size

    to the principal peak in the

    chromatogram obtained with the

    reference solution(a)

     

     

     

     

     

     

    Conforms to regulation

     

     

     

     

     

     

     

     

     

    TE

    ST

    S

     

     

     

     

    composition

     

    Principal peak:minimum 80 per cent  ;

    Except for I peak:which can be

    maximum 10 per cent ;Any other

    peak:for each peak, maximum 5 per

    cent

     

    Principal peak:87per cent;Except for

    I peak:which can be 7 per cent  ;Any

    other peak:for each peak, 3per cent

     

     

     

    Conforms to regulation

     

    Ethylene oxide

    maximums 1ppm

     

    Conforms /to regulation

     

    Conforms to regulation

     

    Loss on drying

    maximums 5 per cent

    1.5%

     

    Conforms to regulation

     

    Sulphated ash

    maximums 0.4 per cent

    0.15%

     

    Conforms to regulation

     

    Heavy metals

     

    maximums 20ppm

     

    Conforms to regulation

     

    Conforms to regulation

     

    Cadmium

     

    maximums 1 PPM

     

    Conforms to regulation

     

    Conforms to regulation

     

    Lead

     

    maximums 3 PPM

     

    Conforms to regulation

     

    Conforms to regulation

     

    Mer.cur.y

     

    maximums 0. 1 PPM

     

    Conforms to regulation

     

    Conforms to regulation

     

    Arsenic

     

    maximums 1 PPM

     

    Conforms to regulation

     

    Conforms to regulation

     

     

     

    Total plate count

     

    Less than 1000CFU/G

     

    Less than 1000cfu/g

     

    Conforms to regulation

     

    Yeast&Mould

     

    Less than 100CFU/G

     

    Less than 100cfu/g

     

    Conforms to regulation

     

    E.coli

     

    Absent

     

    Absent

     

    Conforms to regulation

     P.aeruginosa

     

    Absent

     

    Absent

     

    Conforms to regulation

     

    Methanol

    maximums 0.3 per cent

    0.015%

     

    Conforms to regulation

     

    assay(dried substance)

    95.0%~105.0%    95.0  percent to105.0 percent

    98.5%

     

    Conforms to regulation

     

    conclusion

     

    based on    EP     Inspection ,Conforms to regulation

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