We use cookies to help provide you with the best possible online experience. Please read our Privacy Policy for information about which cookies we use and what information we collect on our site. By continuing to use this site, you agree that we may store and access cookies on your device.
One More Step to Finalize Your Registration
An activation link has been sent to your email address.
Please check the email and activate your account now. It might take few minutes to get the email.
If you did not find it, please check your spam box.
Having problem receiving the email? Send again
Still cannot receive? Contact us
Email :PharmaSources@imsinoexpo.com
Whatsapp :+86-13621645194
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Sample Provided: no
Appearance and properties: white to light yellow powder
Density: 1.252 g/cm3
Melting point: 199-203 ° C
Boiling point: 526 ° C at 760 mmHg
Flash: DHS 271.9 C
Stability: Stable. Incompatible with strong oxidizing agents, acids.
Storage condition: 2-8 ° C
Trimethoprim is a bacterial dihydrofolate reductase inhibitor, a sulfanilamide synergistic drug. The principle of its antibacterial action is to interfere with folate metabolism of bacteria. It mainly selectively inhibits the activity of dihydrofolate reductase of bacteria, so that dihydrofolate cannot be reduced to tetrahydrofolate, thus inhibiting the growth and reproduction of bacteria. Trimethoprim has antibacterial activity against most gram-positive and gram-negative bacteria. In addition, trimethopridine has a certain effect on plasmodium and some fungi, such as nocardia, protozoa and yeast. Among gram-positive bacteria, streptococcus pneumoniae is sensitive to trimethoprim. Among the gram-negative bacteria, escherichia coli, salmonella, proteus, pneumoniae, dysentery, typhoid and pertussis are sensitive to trimethophenil. Trimethoprim has no antibacterial effect on pseudomonas aeruginosa, meningococci and alkali-producing bacillus.