Basic Info
  • Grade: Food Grade

    Factory Location: China

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: NA

    Packaging Information: NA

  • Delivery Lead Time: 10-30days

    Sample Provided: yes

    Payment Terms: TT; L/C;

    Tipiracil CAS Number 183204-72-0 Molecular Formula C9H12Cl2N4O2 Molecular Weight 183204-72-0 Package:1 Kg/Bag Function: thymidine phosphorylase inhibitor Application: For research use only Tags: Anti Tumor New Products.

    Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials.

    TAS-102 is an antitumor agent composed of a combination of trifluorothymidine (FTD), a nucleoside that incorporates into DNA and inhibits a variety of genetic functions required for the proliferation of cancer cells, and tipiracil hydrochloride (TPI), an inhibitor of thymidine phosphorylase (which degrades FTD) that maintains an effective blood concentration of FTD. Tipiracil protects trifluridine from being broken down when taken orally.

    Seebio also can supply Tipiracil intermediates as below:

    PRODUCT NAME CAS NO. USAGE
    5-Chloro-6-(chloromethyl)-2,4(1h,3h)-pyrimidinedione 73742-45-7 Tipiracil
    3,4-dihydro-2H-pyrrol-5-amine hydrochloride (1:1) 7544-75-4 Tipiracil
    6-(Chloromethyl)uracil 18592-13-7 Tipiracil

    Thank you for your attention to Seebio Biotech (Shanghai) Co., Ltd.. If you’ve got any questions or comment, please

    contact us by phone, fax or email, as well as in letter.

    • Name: Tipiracil HCl 
      CAS#: 183204-72-0 
      Chemical Formula: C9H12Cl2N4O2 
      Exact Mass: 278.03373 
      Molecular Weight: 279.12318 
      Elemental Analysis: C, 38.73; H, 4.33; Cl, 25.40; N, 20.07; O, 11.46
      Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
      Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
      Solubility: Soluble in DMSO, not in water
      Shelf Life: >2 years if stored properly
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