The Panaxadiol Saponins

Product Name                        The Panaxadiol Saponins

Latin Name in Botany           Panax ginseng C.A. Meyer

Family                                      Araliaceae

Genus                                      Panax

The Used Part                         Root

Introduction

The main components of ginseng are ginsenosides. Our scientists have separated 39 kinds of ginsenosides from ginseng. In addition to ginsenosides, ginseng also contains ginseng polysaccharide, ginseng protein, ginseng volatile oils, amino acids, inorganic elements, peptides, and a variety of vitamins, organic acids, alkaloids, fats, flavonoids, enzymes, sterols, nucleosides, lignin and other substances. The ginsenoside have a similar basic structure, ginsenoside contain steranes steroid nucleus which includes 30 carbon atoms arranging in four rings. Depending on the different glyco-based architecture, ginsenoside are divided into two groups: dammarane and oleanane. The dammarane type includes two categories: panaxadiol, type - A type, glycosides was 20 (S)-. The Protopanaxadiol contains most ginsenosides, such as ginsenoside Rb1, Rb2, Rb3, Rc, Rd, Rg3, Rh2 and glycoside-based PD; Ginseng triol type-B type and glycosides was 20 (S). The original panaxatriol contains ginsenoside Re, Rg1, Rg2, Rh1 and the glycosidic based PT; oleanane type: oleanolic acid type-ctype, daidzein oleanolic acid.

Character

Light yellow or off-white powder.

Available specification

Rb1+Rc+Rb2+Rb3+Rd>60%HPLC

Purity>90%

Pharmacological function

  1.  Ginsenoside Rb1: suppress the central nervous system; engage myocardial ischemia-reperfusion operating role, with the potential effect in the animal testicles, which also affects the embryonic development of mice; enhance cholinergic function and increase the synthesis and release of acetylcholine and improve memory effect.

2.  Ginsenoside Rb2: promote the synthesis of DNA, RNA, and suppress the central nervous system; reduce intracellular calcium, antioxidant; remove free radicals and improve myocardial ischemia-reperfusion injury.

3.  Ginsenoside Rb3: enhanced myocardial function; protect the body's own immune system; be used to treat a variety of different causes myocardial contractile failure.

4.  Ginsenoside Rc: the steroidal molecules in a ginseng. To suppress cancer cells, increase sperm motility.

5.  Ginsenoside Rd: suppress the central nervous system, anti-fatigue, analgesic, sedative, antipyretic, and promote serum protein synthesis. Rh1 can promote hepatocyte proliferation, DNA synthesis, and can be used for the treatment and prevention of hepatitis, cirrhosis of the liver.

6.  Ginsenoside Rg3: role in the G2 phase of the cell reproductive cycle, inhibit cancer cell mitosis early proteins and ATP synthesis, slow down the growth rate of the proliferation of cancer cells, and inhibit tumor cell invasion, anti-tumor cell metastasis promote tumor cell apoptosis, inhibit tumor cell growth.

7.  Ginsenoside Rh2: inhibit cancer metastasis to other organs; enhance immunity, and quickly restore the constitution. Anti-metastatic cancer, with surgery taking, enhanced wound healing after surgery and physical recovery. Reduce acetylcholine caused contraction of isolated guinea pig uterus.

Applications

Medicine, Health food and beverage, Cosmetics