Tenofovir Alafenamide fumarate (TAF)

Category:Active Pharmaceutical Ingredients
Product Name:Tenofovir Alafenamide fumarate (TAF)
CAS No.:1392275-56-7
Standard:In-house Standards
Price(USD):Negotiable
Company:Changzhou Comwin Fine Chemicals Co., Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Hubei

    Main Sales Markets: Central/South America,Western Europe,Eastern Europe,Asia,Middle East

  • Monthly Production Capacity: 1MT

    Packaging Information: 1kg/drum, 5kg/drum

  • Delivery Lead Time: 2 weeks

    Sample Provided: yes

    Tenofovir alafenamide fumarate is a lipophilic prodrug of tenofovir which is preferentially metabolized in lymphatic tissue resulting in high concentrations of tenofovir (TFV) and its active diphosphate metabolite inside the cells that replicate HIV. Due to its selectivity for these tissues, lower total doses of TAF can be administered relative to tenofovir disoproxil fumarate (TDF) which results in improved bone and renal biomarkers. Tenofovir alafenamide fumarate has become the "backbone" of multiple combination products for the treatment of HIV, combined with emtricitabine for PreP and as a monotherapy for the treatment or HBV.

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