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Category:Active Pharmaceutical Ingredients > Hormones
Product Name:Sermaglutide Powder CAS 910463 68 2
CAS No.:910463 68 2
Standard:In-house Standards
Price(USD):US$1075~US$1180/g
Company:HANGZHOU HUADI GROUP CO., LTD.
Grade: Pharmaceutical Grade
Factory Location: anji Huzhou city china
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia
Monthly Production Capacity: 100gm
Packaging Information: 200mg/500mg/1g/10g/50g/100mg per package
Delivery Lead Time: 7 days after order confirmed
Sample Provided: yes
Payment Terms: T/T
Synthetic Sermaglutide Powder CAS 910463 68 2
Introduction:
Semaglutide, sold under the brand name Ozempic among others, is an antidiabetic medication used for the treatment of type 2 diabetes and long-term weight management.[15][16][17]
Semaglutide acts like human glucagon-like peptide-1 (GLP-1) in that it increases insulin secretion, thereby increasing sugar metabolism. It is distributed as a metered subcutaneous injection in a prefilled pen, or as an oral form. One of its advantages over other antidiabetic drugs is that it has a long duration of action, so a once-a-week injection is sufficient.[18]
An injectable version (Ozempic) was approved for medical use in the United States in December 2017,[19] and in the European Union,[12] Canada,[20] and Japan in 2018. A version which is taken by mouth (Rybelsus) was approved for medical use in the United States in September 2019,[21] and in the European Union in April 2020.[13] It is the first glucagon-like peptide receptor protein treatment approved for use in the United States that does not need to be injected.[22] It was developed by Novo Nordisk. Side effects include nausea, vomiting, diarrhea, abdominal pain, and constipation.[9]
In June 2021, the US Food and Drug Administration (FDA) approved semaglutide injection sold under the brand name Wegovy for long-term weight management in adults
Currently, several drugs commonly used in clinical treatment of premenopausal breast cancer and prostate cancer by ovarian removal (referred to as GNRH-A drugs)
Semaglutide is a new generation of glP-1 chemicalbook (glucagon-like peptid-1) analogue developed by NovoNordisk, Denmark. Semaglutide is a long-acting formulation based on the basic structure of liraglutide, which is better for the treatment of type 2 diabetes
Fuction &Application:
Semaglutide is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes.[9][10]
Semaglutide may be administered in combination with other antidiabetic drugs; dose of concomitant insulin or sulfonylurea may need to be reduced.[23]
Semaglutide (Wegovy) is also indicated as an adjunct to diet and exercise for long-term weight management in adults with obesity (initial body mass index (BMI) ≥ 30 kg/m2) or overweight (initial BMI ≥ 27 kg/m2) with at least one weight-related comorbidity.
Certificate of Analysis
Product Name |
semaglutide |
Batch No. |
210201 |
Mfg. Date |
Feb 22, 2021 |
Exp. Date |
Feb 21, 2023 |
Sequence: His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEA-AEEA-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
molecular formula:C187H291N45O59, molecular weight:4113.57754 |
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Test |
Specification |
Results |
Appearance |
White powder |
Conforms |
Solubility |
Soluble in water |
Conforms |
Purity (HPLC) |
NLT 98.0% |
99.5% |
Acetic Acid |
NMT 8% |
0.4% |
Mass spectrum |
4113.58±1 | 4113.58±1 |
Peptide content (N%) |
NLT80% |
94.8% |
Residual solvent
Wate Content (Karl Fischer) |
Methanol≤3000ppm Acetonitrile≤410ppm Triethylamine ≤320ppm
NMT7.0% 4.6% |
ND . 136ppm ND |
Storage:In an air tight container,protected from light at temperature2-8℃. Conclusion:the product complies with enterprise standard.
Not for human use without further processing.
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