Saxagliptin

Name: Saxagliptin
Availability: saxagliptin-261136.html

Category:Active Pharmaceutical Ingredients
Product Name:Saxagliptin
CAS No.:361442-04-8
Standard:ChP, USP, BP, EP
Company:Rensin Chemicals Limited

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Basic Info

Grade: Pharmaceutical Grade

Factory Location: China

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East,Africa
Sample Provided: no

Payment Terms: L/L

Saxagliptin inhibits dipeptidyl peptidase 4 (DPP-4) enzyme resulting in prolonged active incretin levels. Incretin hormones (eg, glucagon-like peptide-1, glucose-dependent insulinotropic polypeptide) regulate glucose homeostasis by increasing insulin synthesis and release from pancreatic beta cells and decreasing glucagon secretion from pancreatic alpha cells. Decreased glucagon secretion results in decreased hepatic glucose production. Under normal physiologic circumstances, incretin hormones are released by the intestine throughout the day and levels are increased in response to a meal; incretin hormones are rapidly inactivated by the DPP-4 enzyme.

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