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Rutin is a flavonol compound quercetin rutinoside, is a flavonoid extracted from plants, found in rue, buckwheat, locust buds, catalpa leaves, tomato stems, leaves and seed shells, etc., dry buckwheat when about to bloom contains about 3%, jujube, hawthorn, ginkgo, goji berry, motherwort, saihu, summer hay, aloe vera, gynostemma, etc. all contain rutin. In the legume Sophorajaponica L. The content of locust rice can reach more than 20%, which is the main raw material for extracting rutin in China's pharmaceutical industry. Rutin can be decomposed with water when it is strongly acidic and alkaline. It is unstable in color in alkaline foods and has antioxidant capacity. In ethanol, it can improve the light fastness of pigment preparations, prevent the gradual disappearance or change of aroma, and combine with vitamin E to improve its antioxidant capacity. The inhibition of lipid peroxidation of rutin is related to its enhancement of SOD activity and oxygen radical scavenging. Xia Weimu et al. found that rutin has a strong scavenging effect on O2-, and the removal efficiency of Chemicalbook can reach more than 96%. As a chelating agent of Fe2+, rutin can inhibit the Fenton reaction and the chain reaction of lipid peroxidation and has obvious anti-lipid peroxidation effect. A variety of rutin health foods have been developed abroad. Sophora rice has a strong antioxidant effect on edible oil. The scavenging rate of free radicals can reach 40%~70%, which can be used as a new edible oil and fat-containing food additive with health care function, and can also be used for cold drinks, beverages, pastries, processed meat, and processed aquatic products. Buckwheat rutin health care factor has the effect of lowering blood lipids, lowering blood pressure, lowering urine sugar and losing weight, and has been developed into delicious and convenient snacks (buckwheat tea, buckwheat rice, buckwheat noodles, etc.). Rutin was hydrolyzed with 2% dilute H2SO4 for 1h, cooled and filtered to precipitate, washed and dried, and crude products were recrystallized by ethanol to obtain fine quercetin. If other flavonoids such as quercetin are mixed with α-tocopherols or catechins, the addition effect can be shown.
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Pharma Sources Insight June 2024: Globalization on the Go
