Retinyl Retinoate

Product description

Retinyl Retinoate is a new type of vitamin A derivative with higher activity and no fear of light perception. The VA derivative used in the nano-encapsulated AA ester is Retinyl Retinoate, which is compounded with vitamin C through nano-encapsulation;

Retinyl Retinoate is a new type of vitamin A derivative with higher activity and no fear of light perception. The VA derivative used in the nano-encapsulated AA ester is Retinyl Retinoate, which is compounded with vitamin C through nano-encapsulation; retinyl retinoate is obtained by the esterification of the hydroxyl group of retinol and retinoic acid. , while avoiding the limitations of retinol and retinoic acid in cosmetic applications; the particle size of the nano-encapsulated AA ester is 230-300 nm. On the one hand, the nanoemulsion of this particle size can stably suspend the active substance in the nano-carrier, and at the same time It can make the active substance penetrate into the skin effectively and control the release speed of the active substance.

Product Details Form

Function

1. Promote the renewal rate of the skin surface layer, make the skin surface layer more compact and orderly

2. Promote the accelerated production of collagen in the dermis and inhibit the destruction of collagen by MMP

3. Increase the content of mucopolysaccharides (such as hyaluronic acid, etc.) in the epidermis to make the skin more water-retaining

4. Promote the metabolism of the stratum corneum, make the stratum corneum firmer, and restore the barrier function

5. Use around the eyes to significantly reduce wrinkles and fine lines around the eyes;

6. Protect the skin from UV damage and improve the dry, rough and fine lines of the skin caused by UV;

7. Inhibit tyrosinase activity.

Application

Anti-aging product: maintains collagen in the dermis and prevents collagen from degrading too quickly. Formulated with hyaluronic acid and bio-complex polysaccharide (hydrolyzed myrtle), the improvement of fine lines can be observed within a week.

Whitening products: cooperate with VC to inhibit tyrosinase, promote metabolism, and accelerate the disappearance of melanin. The literature shows that it is equally effective to treat acne skin with VC.

Sunscreen products: Inhibit the enhancement of MMP activity caused by ultraviolet rays, protect elastin and dermal collagen, and improve wrinkles and fine lines caused by UV exposure.

Repair products: Promote the synthesis of hyaluronic acid in the body, reduce skin TEWL, promote keratinocyte activity, increase the thickness of the epidermis, and make the epidermis stronger.

Test

Retinyl Retinoate promotes the expression test of mucopolysaccharide (hyaluronic acid) in vivo: 0.05% retinol group, 0.05% retinoic acid group, and three control groups are set for the skin of mice after hair removal treatment Three days later, the binding of hyaluronic acid and protein (HABP) in the epidermis and dermis of mouse tissue sections was observed to have a staining reaction.

Main Feature:

Cytotoxicity: IC 50 retinol 25μM, retinol retinoate 40μM (60% higher than retinol), prohibited for personal care (IC 50 is a certain concentration of a substance that induces 50% apoptosis The amount is used to measure the ability of the substance to induce apoptosis. The higher the cytotoxicity, the weaker the cytotoxicity);

Biological activity: Retinol retinoate retains the ring end group and side chain alkenyl group, and still has the biological activity of retinol and retinoic acid,

In vivo tests show that: the ability to promote skin regeneration is better than retinol and retinoic acid;

Improves the optical stability and chemical stability of retinol, while reducing the irritation of retinol and retinoic acid.

Company introduction and certificates obtained

Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.