Recombinant Protein IGF-1 LR3

 Recombinant Protein IGF-1 LR3

WHAT IS IGF-1/LR3

IGF-1 is polypeptide long-chain amino acid peptide hormone. Insulin-like Growth Factor (Long-R3 IGF-1), an 83 amino acid analog of IGF-1 is a highly anabolic hormone released primarily in the liver with the stimulus of growth hormone (HGH).

IGF-1 is a peptide molecule and is about the same size and structure as insulin. IGF hormone analogs are known as growth factor polypeptide hormones. In the body, IGF-1 is released in the presence of Human Growth Hormone and functions to promote nitrogen retention and increases in protein synthesis. Growth peptides cause a direct effect on muscles in the body by actual development of fresh muscle fibers and cells.

Many believe in the value of using IGF to promote muscle building. It is thought that it anything it does not cause the loss of muscle. It is often used in addition to other therapy by bodybuilders to enhance exercise potential and improve physique.

Application

LONG® R3 IGF-I human has been used:

• for the in vitro direct stimulation of pancreatic islets
• as a component of growth medium for retinal cell lines
• to culture vascular smooth muscle cells (VSMCs)

LONG® R3 IGF-I is a recombinant analog of human insulin-like growth factor-I (IGF-I) that has been specifically engineered for the enhancement of cell culture performance. It is more biologically potent in vitro than either insulin or native IGF-I and has been shown to significantly increase recombinant protein production. It is ideal for both research and large-scale culture systems utilizing serum-free or low-level serum applications. LONG R3 IGF-I has been used with numerous cell types including CHO, vaccine-producing cell lines, fibroblasts and stem cells. All cell types that have a growth response to insulin in cell culture have the potential to respond to LONG R3 IGF-I. LONG R3 IGF-I provides equivalent or better performance to recombinant insulin depending on the cell line and clone.

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