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Pyruvate is a component of the human body, which is mainly involved in the metabolism of sugars, fats, etc. in the human body, and is also one of the intermediate products of carbohydrate metabolism. Pyruvate and the salts it produces are widely used in the field of medicine, such as the production of sedatives, antioxidants, antivirals, synthetic drugs for the treatment of hypertension and so on. Pyruvate is also known as acetalic acid, pyro-grapeic acid, 2-oxopropionic acid. Light yellow to yellow transparent liquid. There is an acetic acid odor. There is a sour taste. Natural products are found in mint and sucrose fermentation broth. The relative molecular mass is 88.06. The relative density is 1.2271. Melting point 13.8 °c. Boiling point 165 °C (decomposition), 106.5 °C (13.332×103Pa), 85.3 °C (5.333×103Pa), 70.8 °C (2.666×103Pa), 57.9 °C (1.333×103Pa), 45.8 °C (0.667×103Pa), 21.4 °C (0.133×103Pa). Flash point 82 °c. The refractive index is 1.4280. Miscible with water, ethanol, ether, etc. The color darkens in the air. Slow polymerization when heated, rich in reactivity, easy to react with nitride, aldehyde, halide, phosphide, etc., participate in the biochemical synthesis of organisms, colloids, amino acids, proteins, etc., metabolism, alcohol fermentation and other Chemicalbook. When exerted, it is reduced to lactic acid in the muscles, oxidized again at rest and partially converted to glycogen. Rats have oral LD502100mg/kg. Uses: for the synthesis of medicine, amino acids (L-tyrosine substrates), etc., can improve efficiency, especially in the pharmaceutical industry can shorten the process, simplify the process, such as 2-phenylcinchonine acid made with this product, is an antipyretic analgesic, diuretic, the use of this product as raw materials, can greatly reduce production costs; In addition, it is also used as anti-tuberculosis drugs, calcium isoniazid, pyruvate synthesis, hormone synthesis, insect repellent pyrunium pamote (Pyruniumpamote) raw materials; Also used for pesticide raw materials; Using pyruvate, indole and ammonia as raw materials, biochemical reactions can be carried out to produce tryptophan; To produce monosodium glutamate, in order to improve the yield of L-threonine, this product can be used; Spices are edible spices allowed to be used in China's GB2760-1996 regulations. Preparation method: 1, acetone ester is prepared by gas or liquid phase oxidation of lactate as raw material, and can be prepared by further hydrolysis. 2, with tartaric acid as raw material, add potassium bisulfate and sodium bisulfate, heat to 210~220 °C, dehydrogenation, can obtain crude pyruvate product, and then use vacuum rectification to refine. 3, using 2,2-dichloropropionic acid as raw material, using sodium hydroxide, adjusting pH=6, hydrolysis, can be prepared.
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