Propylgallate Injection

【 ingredients 】 chemical name: the product ingredient for Bang propyl ester, its chemical called three, four, five, three hydroxy benzoic acid ester c.

Accessories: sodium metabisulfite, cysteine hydrochloride, in accordance with the acid disodium, propylene glycol (for injection).
【 characteristics 】 this product is colorless or nearly colorless transparent liquid or viscous liquid.
【 indications 】 used for prevention and treatment of cerebral thrombosis, coronary heart disease and the complications after the surgery, thrombotic phlebitis, etc.
【 specification 】 (1) 5 ml: 60 mg (2) 10 ml: 120 mg 【 usage and dosage 】 to 250 ~ 500 ml saline solution or 5% glucose injection intravenous drip slowly.
Once a day, a 120-180 mg, 10 ~ 15 days for a course of treatment.
Or as directed by physician.
【 side effect 】 after intravenous drip a few patients increased heart rate slow down or Alt mild sex and stop drug can return to normal within 1 ~ 2 weeks.
【 taboo 】 this article allergy to any ingredient is disabled.
【 precautions 】 1.
This product during the medication should check liver, kidney, if there are any exception, should stop drug, to continue to use after returning to normal.
2.
When static drop speed should not be too fast, can prevent occurrence palpitate, dizziness, fatigue and other symptoms.
3.
During the use of this product, if appear any adverse events and/or adverse effects, consult a doctor.
4.
The use of other drugs at the same time, please inform the doctor.
5.
Please placed in children can not touch.
Pregnant women and nursing mothers medication 】 【 it is not clear on the safety of pregnant women and nursing mothers.
And there is no medicine for children 】 【 this product children's medication safety research materials.
Lack of elderly medication 】 【 【 elderly patients medication safety research materials.
See other content under when using, or as directed by the doctor's advice.
[drug interaction] and there is no drug interaction of research data.
And there is no drug overdose 】 【 this product reports of drug overdose.
In the event of drug overdose, should immediately stop drug, giving support and symptomatic treatment.

Pharmacology and toxicology 】 【 1.
Pharmacological effects of this product has the inhibition of thromboxane A2 (TXA2) caused by platelet aggregation;
Can be lower than than the whole blood viscosity and plasma viscosity, speed up the RBC electrophoresis, can also relax vascular smooth muscle, increase coronary blood flow;
Have obvious protective effect on myocardial ischemia.
2.
Toxicity research acute toxicity experiment, intravenous LD50 in mice was 311.13 mg/kg + / - 5.31 mg/kg.
Subacute toxicity experiments show that the product had no obvious effect on liver and kidney functions.
Ames test negative.
After intravenous injection in vivo pharmacokinetic 】 【 highest concentration distribution in liver, lungs, heart kidney.
Through the blood - brain barrier.
Mainly from the urine excretion and blood elimination half-life is 100 minutes.
【 storage 】 shading, airtight, (no more than 20 ℃) to save in the shade, avoid freezing.
【 packing 】 ampoule.
(1) 5 ml: 60 mg, 2 / box, 5 pieces/box, six/box, 10 / box.
(2) 10 ml: 120 mg, 2 / box, 5 pieces/box, 10 / box.
The period of validity 】 【 18 months.
[standards] WS1 - XG - 008-2014 (1) approval number 】 【 5 ml: 60 mg H20050377 approved by the state (2) 10 ml: 120 mg H20050378 approved by the state