Procaine HCL,Benzocaine,Meprobamate, Nifuratel,Gastrodin.

Procaine hydrochloride is a kind of local anesthetic, which can temporarily block the conduction of nerve fibers and has anesthetic effect. It has strong effect, low toxicity and no addiction. But it has weak penetration to skin and mucous membrane and is not suitable for surface anesthesia. Clinically, it is mainly used for infiltration, spinal and conduction anesthesia. The aqueous solution of this product is stable at pH 3.0 ~ 5.0. Therefore, when preparing procaine hydrochloride injection, it is generally necessary to add acid to adjust the pH value between 3.3 and 5.5, and strictly control the sterilization temperature and time. It is appropriate to sterilize procaine hydrochloride injection at 100 ℃ for 30min, and pay attention to shading and sealed storage. In dilute hydrochloric acid, the aromatic primary amino group in the structure of the product forms diazonium salt with sodium nitrous acid, and then adds alkali β- The coupling reaction of naphthol produces scarlet azo compounds. Properties procaine hydrochloride is white fine needle crystal or crystalline powder at room temperature, odorless, slightly bitter and numb, easily soluble in water, soluble in ethanol, slightly soluble in chloroform, almost insoluble in ether. The ester bond in the structure of procaine hydrochloride can be hydrolyzed to form p-aminobenzoic acid and diethylaminoethanol. Under certain conditions, p-aminobenzoic acid can be further decarboxylated to form toxic aniline. Procaine hydrochloride has aromatic primary amino groups in its structure, which is easy to oxidize and discolor. PH value, temperature, ultraviolet, oxygen and metal ions can accelerate the oxidation discoloration.