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Therapeutic indications
indicated for the treatment of neuropathic pain in adults .and It is indicated as adjunctive therapy in adults with partial seizures with or without secondary generalisation.
Dose and method of administration
The dose range is 150 to 600 mg per day given in two divided doses.may be taken with or without food.
Neuropathic Pain
treatment can be started at a dose of 150 mg per day, given as two divided doses. Based on individual patient response and tolerability, the dosage may be increased to 300 mg per day, given as two divided doses, after an interval of 3 to 7 days, and if needed, to a maximum dose of 600 mg per day after an additional 7-day interval.
Epilepsy treatment can be started with a dose of 150 mg per day given as two divided doses. Based on individual patient response and tolerability, the dosage may be increased to 300 mg per day given as two divided doses after 1 week. The maximum dosage of 600 mg per day given as two divided doses may be achieved after an additional week.
Hepatic Impairment
No dosage adjustment is required for patients with hepatic impairment
Children and Adolescents (<18 years)
The safety and effectiveness of pregabalin has not been established in patients below the age of 18 years, with either epilepsy or neuropathic pain.
Elderly (>65 years)
No dosage adjustment is necessary for elderly patients unless their renal function is
compromised