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Category:Intermediates > Chiral Intermediates Product Name:Pramiracetam CAS No.:68497-62-1 Standard:USP Price(USD):0.00 Company:SHANXI YONGJIN GROUP CO LTD
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 1000kg
Packaging Information: As required
Sample Provided: yes
Payment Terms: TT/LC
Product Name:pramiracetam
Other Name:Pramiracetam Hydrate丨Amacetam丨N-[2-(Diisopropylamino)ethyl]-2-(2-oxo-1-pyrrolidinyl)acetamide
Molecular Formula:C14H27N3O2
Molecular Weight:269.383
Use:Pramiracetam is a nootropic drug derived from piracetam, and is more potent. Pramiracetam reportedly improved cognitive deficits associated with traumatic brain injuries. IC50 Value: Target: in vitro: Pramiracetam sulfate did not exhibit any affinity in vitro for dopaminergic , GABAergic, serotoninergic, adrenergic, muscarinic, adenosine (IC50 > 10 uM), and benzodiazepine receptors (IC50 > 1 uM) binding sites [1].in vivo: In a double-blind, randomized design, two groups of six subjects each received alternating placebo and single 400, 800, 1,200, and 1,600 mg oral doses of pramiracetam after an overnight fast. Mean (+/- SD) peak plasma concentrations of the four dose groups (2.71 +/- 0.54, 5.40 +/- 1.34, 6.13 +/- 0.71, 8.98 +/- 0.71 micrograms/mL) were attained between two to three hours following drug administration [2]. Two doses of pramiracetam (7.5 mg/kg and 15 mg/kg) were administered daily prior to testing for 7 weeks in a 16-arm radial maze in which nine arms were baited with food [3].