Pralidoxime iodide

This product for organophosphorus pesticide poisoning antidote, with mild organophosphate poisoning, can be used alone tropic o this product or to control the symptoms;
Moderate and severe poisoning must be combined application of atropine, due to the accumulation of body has little effect of acetylcholine.
After intravenous administration, blood soon achieve effective concentration, large doses can also through the blood-brain barrier into the brain tissue, through the kidney soon, no accumulation poisoning phenomenon.When organic phosphate ester insecticidal agent (such as dichlorvos, 1609, 1059, etc.) after entering the body, combined with cholinesterase in the body, form phosphorus acylation enzyme, the role of the cost of the hydrolysis of acetylcholine, thus in the accumulation of acetylcholine, a series of poisoning symptoms.
Pralidoxime iodide solution such as poison in the body with phosphorus acylation of cholinesterase phosphoryl knot, the free will of cholinesterase, restore the activity of the hydrolysis of acetylcholine, therefore is also called the cholinesterase complex agent.
Pralidoxime iodide and can combine with blood organophosphate class directly, become a non-toxic material from the urine.