Polylysine Powder

About The Detailed Introduction Of Polylysine?

Polylysine powder is highly hygroscopic and slightly bitter. It is a linear polymer of lysine. It was first discovered in 1977 by Japanese scholar S. Shima and H. During the screening of microorganisms, Sakai found that it is produced by fermentation of Streptomyces and has a broad-spectrum antibacterial effect. It is polymerized from 25-30 lysine groups and is relatively stable to pH and heat. Its antibacterial effect is related to the degree of polymerization and the environment. The best antibacterial activity is between 3600-4300 molecular weight. At the same time, its hydrolyzate is lysine necessary for the human body, so polylysine is called a nutritional bacteriostatic agent. It was used in food preservatives in the 1980s, but it has not been used in my country for a long time. In 2014, the former National Health and Family Planning Commission approved ε-polylysine as a new food additive. As a natural preservative, it has unique application conditions. Similar to nisin, the benchmark natural preservative, both are polypeptide preservatives, and polylysine has a wider antibacterial range than nisin. Most natural preservatives have a good antibacterial effect on Gram-positive bacteria, but have no obvious effect on Gram-negative bacteria such as Escherichia coli. The emergence of polylysine breaks this "hidden rule". It also has obvious antibacterial and killing effects on Gram-negative bacteria such as Escherichia coli and Arthrobacter, and has outstanding broad-spectrum antibacterial effects.

Product Details List

Product Features

ε-polylysine (ε-poly-L-lysine, referred to as ε-PL) is produced by Streptomyces albulus through liquid deep aerobic fermentation and contains 25 to 35 L-lysine residues. The homomeric monomer polymer has obvious inhibitory effects on Gram-positive and Gram-negative bacteria, yeasts, molds, viruses, etc., and is widely used in food, daily chemical, pharmaceutical and other industries. This substance can be completely digested and absorbed by the human body and decomposed into lysine necessary for the human body without any toxic or side effects.
1. Broad Antibacterial Spectrum: can effectively inhibit Gram-positive and Gram-negative bacteria, yeasts, molds, viruses and other microorganisms.
2. High Temperature Resistance: It does not decompose under high temperature environment (121℃, 30 minutes), so it can participate in the heat treatment process of products and be processed together with raw materials.
3. Strong Water Solubility: ε-polylysine is easily soluble in water, with a maximum solubility of at least 500g/L.
4. Wide PH Range: Under pH 2 to 9 conditions, ε-polylysine has strong bactericidal ability, which can make up for the shortcomings of other preservatives’ low activity under neutral and alkaline conditions.
5. Strong Synergy: As a new type of food preservative and bactericide, ε-polylysine has good killing effect when used alone, and can be paired with other food additives (such as vinegar, ethanol, glycine, organic acids, etc.) It can be used more synergistically and greatly improve the killing effect.
6. High Safety: The LD50 of polylysine in the acute toxicology test is 5g/kg, which is equivalent to table salt. After the human body ingests polylysine, it can be degraded into lysine nutrients, which can be absorbed and utilized without any toxic or side effects.
7. It Has Health Care Functions: Research shows that ε-polylysine can effectively inhibit enzyme activity and fat absorption, thereby reducing the occurrence of obesity.

What Are The Application Directions?

1. Application in food Currently, polylysine powder is widely used in food and beverages, such as cakes, pastries, fast food, butter, salad dressing, beverages, alcohol, meat products, cans, etc. Please refer to the table below for national standard dosages of different types of food. Food classification number Food name Usage amount 07.0 Baked food 0.15g/kg08.03 Cooked meat products 0.25g/kg14.02 Fruit and vegetable juices 0.20g/l In addition, ε-polylysine can also be used as food machinery and containers in food processing enterprises Better cleaning and disinfectant

2. Application in cosmetics and daily chemical products Cosmetics are extremely susceptible to microbial contamination during production, storage and use, leading to corruption. Cosmetics deterioration and mold due to microbial contamination are very harmful to human skin. It has broad-spectrum antibacterial properties and can effectively inhibit the growth of various microorganisms and ensure product quality. Polylysine is a polymer of amino acids and a nutritional preservative, so it is more environmentally friendly, safe and efficient. In addition, polylysine is also widely used in daily chemical products such as toothpaste, mouthwash, soap, hand sanitizer, wet wipes, kitchen cleaning agents, women's sanitary napkins, baby diapers, etc.
3. Application in medicine ε-polylysine is rich in cations, and produces strong electrostatic force with substances containing anions, and has good penetration into biological membranes. Based on this characteristic ε- Polylysine can be used as a carrier for certain drugs and is therefore widely used in medical pharmaceuticals. ε-polylysine polymerizes with methotrexate (a drug used to treat leukemia) to improve the drug's efficacy. Studying the degree of damage of electrical pulses to cell membranes modified with polylysine of different molecular weights, it was found that adsorption of high molecular weight polylysine on the cell membrane would reduce its damage critical voltage.

Company Introduction And Certificates Obtained

Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying Polylysine powder etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.