Pimavanserin Tartrate

Name: Pimavanserin Tartrate
Availability: pimavanserin-tartrate-269706.html

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:Pimavanserin Tartrate
CAS No.:706782-28-7
Standard:ChP, USP, BP, EP, JP
Price(USD):Negotiable
Company:Alicorn Pharmaceutical Co., Ltd

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Basic Info

Grade: Pharmaceutical Grade

Factory Location: Anqing Anhui province

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 100 kgs

Packaging Information: 25kgs per drum
Delivery Lead Time: deliver in two weeks from PO date

Sample Provided: yes

Payment Terms: T/T

Pimavanserin tartrate competitively antagonizes the binding of [3H]ketanserin to heterologously expressed human 5-HT 2A receptors with a mean pKi of 9.3 in membranes and 9.70 in whole cells. ACP- 103 displays potent inverse agonist activity in the cell-based functional assay receptor selection and amplification technology (R-SAT), with a mean pIC50 of 8.7. Pimavanserin tartrate demonstrates lesser affinity (mean pKi of 8.80 in membranes and 8.00 in whole cells, as determined by radioligand binding) and potency as an inverse agonist (mean pIC50 7.1 in R-SAT) at human 5-HT 2C receptors, and lacks affinity and functional activity at 5-HT 2B receptors, dopamine D2 receptors, and other human monoaminergic receptors[1].

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