Phlorizin

What is Phloridzin?

Phlorizin is the glucoside of phloretin. It belongs to dihydrochalcones in flavonoids.

Extracted from apples, apple peels, leaves, etc., it is a phenolic substance in the apple tree. It is a combination of phloretin and glycosides called glucosides. Its degradation product, phloroglucinol, can effectively inhibit microbial activity. Its degradation product, phlobarkol, can effectively inhibit the activities of microorganisms. Clinical studies at home and abroad have shown that phloridizin has good curative effect in treating diabetes.

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What are the benefits?

It has various important biological activities such as lowering blood sugar, improving memory, and anti-oxidation, and has broad application prospects in the development of new drugs and natural health foods.

Antibacterial

Extracted from apples, apple bark and leaves, etc., it is a phenolic substance in the apple tree. Studies have shown that phlorizin accounts for 95% of the total phenolic substances in the apple tree, and its content is very high , so that its existing state can affect the overall existing state of phenolic substances. It is a glycoside formed by combining phloretin and glycosides as glucosides. The glycosyl is hydrolyzed to form glucose, and its high content is considered by many scholars to be a storage form of carbohydrates. 4-deoxyphlorizin has also been widely studied and applied. Its degradation product, phlorobark, can effectively inhibit the action of microbial activities.

Anti-Oxidation

All kinds of flavonoids can eliminate free radicals such as superoxide anion Oˉ2· to a certain extent. This antioxidant ability comes from the hydrogen or electron donating ability of its phenolic hydroxyl group. It is a glycoside derivative of dihydrochalcone phloretin. Dihydrochalcone is one of the members of flavonoids, which has certain antioxidant properties and antioxidant properties. Although its antioxidant activity is weakened due to the glycosidation of the 2'-hydroxyl in the molecular structure, its comprehensive antioxidant capacity is still higher than that of VC and VE, and it has a unique antioxidant mechanism. In addition, it can be hydrolyzed to remove glycosides in the body to generate phloretin, which has better antioxidant capacity.

Treat Diabetes

Recent clinical studies at home and abroad have shown that it also has a good curative effect in the treatment of diabetes. Many scientists use phlorizin when studying the pathogenesis of diabetes and exploring ways to treat diabetes, which makes the research on diabetes treatment go on quickly and smoothly.

Inhibits the transport of glucose molecules by SGLT1 and SGLT2. It has been confirmed in several animal models that it can promote the secretion of glucose, reduce fasting and postprandial blood glucose levels, and do not cause hypoglycemic side effects. Treating diabetic rats can restore their insulin sensitivity to normal and eliminate or alleviate insulin resistance caused by glucose toxicity.

Stimulate Libido

Apple contains a compound called "phlorizin", which has a very similar function to "estradiol", and "estradiol" is an estrogen that plays an important role in the process of sexual arousal. Eating apples can improve female sexual function.

Improve Memory

The activity of the brain consumes a large amount of energy supplied by glucose. Many evidences have proved that the circulating blood sugar level controls the process of learning and memory. The effects of many drugs that improve memory are related to the ability to release liver glycogen, increase brain blood sugar levels and utilize of. Inhibit blood sugar from entering the brain. So the mechanism by which the brain's memory capacity is enhanced is apparently independent of blood sugar levels or the brain's ability to absorb sugar.

What fields can it be applied to?

Food

Phlorizin can be used as an antioxidant added to food. Phloridizin, which is more abundant in apple peel, also has antioxidant effects. Although its antioxidant activity is not as good as that of quercetin, proanthocyanidin, chlorogenic acid and other components in apple polyphenols, because phloridzin has a reduced high The role of blood sugar, if it is used in functional food, can not only achieve the purpose of reducing hyperglycemia, but also solve the problem of food oxidation.

Cosmetic

The antioxidant activity and anti-aging properties of phloridzin have been confirmed by modern scientific research. The hydrolyzed product of phloridzin, phloretin, can competitively inhibit the activity of tyrosinase and interfere with the synthesis of melanin, and its whitening effect is better than many whitening products on the market.

Health products

Phloridzin has the effect of lowering blood sugar and improving memory, so it is widely used in health products

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Company introduction and certificates obtained

YTBIO mainly supplies herbal extracts such as Phlorizin, functional cosmetic raw materials, and organic products. We have many years of R&D and production experience. Committed to the research and development, production and sales of raw materials for the health industry in the 21st century. The certificates obtained so far include ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA etc.