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Email ：PharmaSources@imsinoexpo.com
Whatsapp ：+86-13621645194
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 500kg
Contract Manufacturing: CRO,CMO
Packaging Information: 5kg/drum
Delivery Lead Time: 15days
Sample Provided: yes
Payment Terms: T/T
Description
Vonoprazan Fumarate is the fumarate salt form of vonoprazan, a pyrrole derivative and reversible potassium-competitive acid blocker (P-CAB), with potential antacid activity. Upon administration, vonoprazan specifically and competitively binds to the gastric hydrogen-potassium ATPase (H+/K+ ATPase) proton pump at or, more likely, near its potassium ion (K+) binding site and sterically inhibits K+ binding. This blocks the activation of the H+/K+ ATPase by K+, inhibits the proton pump and prevents gastric acid secretion, thereby lowering gastric acid levels.
Function
Treatment of duodenal ulcer, gastric ulcer and reflux esophagitis, low-dose aspirin-induced gastric ulcer or recurrent duodenal
ulcer.Helicobacter pylori eradication, adjuvant treatment of the following diseases: gastric ulcer, duodenal ulcer, gastric MALT
lymphoma, idiopathic thrombocytopenic purpura, early gastric cancer, Helicobacter pylori-infected gastritis.
One year of qualification
Audited Supplier
Pharma Sources Insight June 2024: Globalization on the Go
