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Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:Pharmaceutical Grade API Relugolix CAS737789-87-6
CAS No.:737789-87-6
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Price(USD):$1000/kg-$2000/kg
Company:Shandong Loncom Pharmaceutical Co.Ltd.
Grade: Pharmaceutical Grade
Factory Location: China
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 500kg
Contract Manufacturing: CRO,CMO
Packaging Information: 5kg/drum
Delivery Lead Time: 15days
Sample Provided: yes
Payment Terms: T/T
Description
Relugolix is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively binds to and blocks the GnRH receptor in the anterior pituitary gland, which both prevents GnRH binding to the GnRH receptor and inhibits the secretion and release of both luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone from Leydig cells in the testes. Since testosterone is required to sustain prostate growth, reducing testosterone levels may inhibit hormone-dependent prostate cancer cell proliferation.
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