Pharmaceutical Grade API Dapoxetine Hydrochloride CAS 129938-20-1

Product Name: Dapoxetine hydrochloride

Chemical Name: 

(S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanamine hydrochloride

CAS NO.: 129938-20-1

Molecular Formula:  C21H23NO.HCl

Molecular Weight: 341.88

Appearance: White to off-white powder 

Standard: 99% 

Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation in December 2004. In October 2005, the company received a FDA Non-Approvable letter from the FDA, at which time they planned to work with regulators to address outstanding questions.