Oxytetracycline Hydrochloride API

Molecular formula: C22H24N2O9·HCl

Properties: Oxytetracycline is used to treat infections caused by Chlamydia (e.g., the chest infection psittacosis, the eye infection trachoma, and the genital infection urethritis) and infections caused by Mycoplasma organisms (e.g., pneumonia). Its hydrochloride is commonly used. Oxytetracycline hydrochloride is yellow crystalline powder, odorless, bitter; it attracts moisture; the color gradually becomes darker when exposed to light, and it is easy to damage and fail in alkaline solution. It is easily soluble in water, slightly soluble in ethanol, and insoluble in chloroform or ether.It is a broad-spectrum antibiotic, and its antibacterial spectrum and principle are basically the same as tetracycline. Mainly has antibacterial activity against gram-positive bacteria and gram-negative bacteria such as meningococcus and gonorrhoeae

Oxytetracycline, like other tetracyclines, is used to treat many infections, both common and rare (see Tetracycline antibiotics group).It is sometimes used to treat spirochaetal infections, clostridial wound infection and anthrax in patients sensitive to penicillin. Oxytetracycline is used to treat infections of the respiratory and urinary tracts, skin, ear, eye and gonorrhoea, although its use for such purposes has declined in recent years due to large increases in bacterial resistance to this class of drugs. The drug is particularly useful when penicillins and/or macrolides cannot be used due to allergy. Many species of Rickettsia, Mycoplasma, Chlamydia, Spirochetes, Amoeba and some Plasmodium are also sensitive to this product. Enterococcus is resistant to it. Others such as Actinomyces, Bacillus anthracis, Listeria monocytogenes, Clostridium, Nocardia, Vibrio, Brucella, Campylobacter, Yersinia, etc. are sensitive to this product.

Oxytetracycline is especially valuable in treating nonspecific urethritis, Lyme disease, brucellosis, cholera, typhus, tularaemia. and infections caused by Chlamydia, Mycoplasma and Rickettsia. Doxycycline is now preferred to oxytetracycline for many of these indications because it has improved pharmacologic features. Oxytetracycline can also be used to correct breathing disorders in livestock. It is administered in a powder or through an intramuscular injection. Many livestock producers apply oxytetracycline to livestock feed to prevent diseases and infections in cattle and poultry. 

Preparations: 5%, 10%, 20%, 30% Oxytetracycline injection; 20% Oxytetracycline HCL soluble powder; Oxytetracycline bolus