Orapani

Name: Orapani
Availability: orapani-343805.html

Category:Active Pharmaceutical Ingredients
Product Name:Orapani
CAS No.:763113-22-0
Standard:In-house Standards
Price(USD):Negotiable
Company:Shanghai Hope-chem Co.,Ltd.

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Basic Info

Grade: pharmaceutical grade

Factory Location: Shanghai

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Eastern Europe,Australasia,Asia,Middle East,Africa
Sample Provided: no

Olaparib is a small molecule inhibitor of ADP ribose polymerase (PARP) with potential chemical sensitization, radiosensitization, and anti-tumor activity. Olaparib selectively binds and inhibits PARP, inhibiting PARP mediated repair of single stranded DNA breaks; The inhibition of PARP may enhance the cytotoxicity of DNA disruptors and potentially reverse the chemotherapy and radiation resistance of tumor cells. PARP catalyzes post-translational ADP nucleosylation of nuclear proteins, which can be activated by single stranded DNA cleavage.

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Orapani

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