Omeprazole Sodium for Injection

DESCRIPTIONS :
Omeprazole Sodium Monohydrate containing Omeprazole sodium monohydrate (equivalent to Omeprazole) is available as sterile injection powder 40 mg for reconstituted and intravenous administration.

INDICATIONS :
Omeprazole Sodium Monohydrate is indicated for :
· Duodenal ulcer
· Gastric ulcer
· Reflux oesophagitis
· Zollinger - Ellison syndrome

DOSAGE AND ADMINISTRATIONS :
Duodenal ulcer, gastric ulcer, and reflux oesophagitis : Patients who cannot be given oral medication can be treated parenterally with Omeprazole 40 mg once daily.  The usual treatment period before transfer to oral treatment is 2 - 3 days.
Zollinger - Ellison syndrome : Dose should be adjusted individually.  Higher doses and/or several daily doses may be required.
IV treatment can be given as injection, whereby the solution for injection must be given slowly over a period of at least 2½ minutes and with a maximum rate of 4 ml/minutes.
Use in the elderly : Dose adjustment is not necessary.
Use in children : There is only limited experience of use in children.
Impaired renal function : Dose adjustment is not necessary.
Impaired hepatic function : In patients with impaired liver function clearance is greatly reduced.