Notoginsenoside

About The Detailed Introduction Of Notoginsenoside?

Notoginsenoside is mainly used to promote blood circulation, remove blood stasis, unblock meridians and activate meridians. It has the effect of inhibiting platelet aggregation and increasing cerebral blood flow, and is used for cerebrovascular sequelae, central retinal vein occlusion, anterior chamber hemorrhage, etc.
It is a natural compound extracted from the roots of Panax notoginseng, also known as total saponins of Panax notoginseng. It is a triterpenoid compound with various biological activities and pharmacological effects.
It has anti-inflammatory, antioxidant, anticoagulant, and blood vessel dilation effects. It can improve the function of the cardiovascular system, lower blood pressure and cholesterol levels, and promote blood circulation. In addition, notoginseng saponins also have immunomodulatory and anti-diabetic effects.
Because of its various pharmacological effects, it is widely used in traditional Chinese medicine preparations, health products, cosmetics and other fields. However, it should be noted that although it is a natural compound, correct medication methods and dosages must be followed when using it to ensure safety and effectiveness.

What Are The Benefits?

Effect On Hyperlipidemia
Clinical study on the lipid-lowering and antithrombotic effects of Notoginsenoside in patients with hyperlipidemia. Results After treatment, the treatment had significant anti-platelet aggregation and fiber-reducing effects, and the clinical efficacy and improvements in blood lipids and blood rheology were better than those in the control group. Studies have shown that total saponins of Panax notoginseng have obvious preventive and therapeutic effects on hyperlipidemia.
Effect On Hyperviscosity
Patients with hyperviscosity were divided into the Panax notoginseng total saponin group and the enteric-coated aspirin group. After 4 weeks of treatment, the results showed that the Panax notoginseng total saponin could significantly reduce platelet surface activity, inhibit platelet adhesion and aggregation, and inhibit platelet adhesion and aggregation. It has the effects of anti-thrombosis and improving microcirculation, and is better than aspirin.
Effect On High Blood Pressure
Treating hypertension with Panax notoginseng saponins, after 20 days of treatment, it can significantly reduce elevated blood pressure and significantly slow down the heart rate. The results show that Panax notoginseng total saponins can significantly reduce MDA, significantly increase SOD, and increase the deformability of red blood cells in patients with hypertension. , reduce the aggregation of red blood cells.
Anti-Myocardial Ischemia Effect
Observation of the effect of total notoginseng saponins on experimental myocardial ischemia found that total notoginseng saponins can significantly improve the ischemic manifestations of surface electrocardiogram, reduce the scope of myocardial infarction, reverse left ventricular diastolic dysfunction in patients with exertional angina, and even Bring it back to normal.
Antiarrhythmic
The antiarrhythmic effect of Panax notoginseng saponins was observed. Animal experiments showed that Panax notoginseng saponins could significantly reduce experimental premature ventricular contractions in rats, significantly shorten the duration of arrhythmias, and significantly reduce reperfusion after acute myocardial infarction in rats. The incidence of arrhythmia.
Anti-Atherosclerotic Effect
Observing the effect of total notoginseng saponins on dietary atherosclerosis in rabbits shows that total notoginseng saponins can play an anti-AS role through anti-inflammatory and antioxidant effects, have a protective effect on vascular smooth muscle cells, and can protect cells from The influence of high-fat serum has a certain preventive and therapeutic effect on the occurrence and development of atherosclerosis.
Anti-Thrombosis, Improve Microcirculation
Studying the effects of total notoginseng saponins on ET-1 and platelet function in patients with coronary heart disease, the results showed that total notoginseng saponins can significantly reduce platelet surface activity, inhibit platelet aggregation and adhesion, anti-thrombosis, and improve microcirculation.
Anti-Cardio-Cerebral Ischemia Effect
Notoginseng total saponins are used to treat cerebral infarction and ischemic cerebrovascular disease. The results show that notoginseng total saponins have a good clinical therapeutic effect on the acute phase of cerebral infarction. Notoginseng total saponins can significantly improve global cerebral ischemia or focal ischemia. Cerebral edema during ischemia-reperfusion.
Promote Hematopoietic Cell Growth
It has a proliferative effect on hematopoietic progenitor cells. Studies have also found that Rg1 and Rb1 in total saponins of Panax notoginseng are effective monomers in promoting hematopoiesis. They can continuously promote the proliferation of human bone marrow granulosa and erythroid hematopoietic progenitor cells, and have an effect on granulosa progenitor cells. More effective than erythroid progenitor cells.
Anti-Fibrosis
Studies at the cellular level have found that Panax notoginseng saponins can delay the process of renal tubular-interstitial fibrosis and improve renal function. Experiments have found that total saponins of Panax notoginseng can delay the onset of alveolitis, make it progress slowly, be mild, and almost not form pulmonary fibrosis.
The effect of Panax notoginseng total saponins on experimental liver fibrosis was studied through animal experiments. The results showed that notoginseng saponins had obvious anti-hepatic fibrosis effects.
Protective Effect Against Nerve Cell Damage
The protective effect of total notoginseng saponins on model cells was observed through the detection of cytology, morphology and lipid peroxidation damage indicators. The results showed that total notoginseng saponins have a protective effect on nerve cell damage caused by energy metabolism disorders.

What Are The Application Directions?

Pharmaceutical Field:

Cardiovascular diseases: Notoginsenoside has anti-platelet aggregation, anti-thrombosis and other effects, and can be used to prevent and treat cardiovascular and cerebrovascular diseases.
Antioxidant and anti-inflammatory: It has obvious antioxidant and anti-inflammatory effects and can be used to treat inflammatory diseases and chronic diseases.
Immunomodulation: It can enhance the body's immune function, regulate the balance of the immune system, and has a certain therapeutic effect on diseases related to immune regulation.

Cosmetics Field:

Anti-aging: It has antioxidant effects, can scavenge free radicals, slow down the skin aging process, and maintain skin elasticity and smoothness.
Whitening and freckle removal: It can inhibit the synthesis of melanin, reduce the occurrence of spots, and make the skin whiter and more even.
Moisturizing: It has moisturizing effect, can increase the moisture content of the skin and improve dry skin.
Food Field:

Functional food: It can be used as functional food additives and has the functions of regulating blood lipids, lowering blood sugar, and enhancing immunity.
Nutritional health products: It can be used as one of the main ingredients of nutritional health products to improve human health.
Other Areas:

Agricultural field: It has antibacterial and anti-insect effects and can be used for plant protection and pest control in agricultural production.
Animal feed field: It can be used as an animal feed additive to improve the immunity and disease resistance of animals.

Company Introduction And Certificates Obtained

Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying Notoginsenoside etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

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