Basic Info
  • Grade: Food Grade

    Factory Location: China

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: NA

    Packaging Information: NA

  • Delivery Lead Time: 10-30days

    Sample Provided: yes

    Payment Terms: TT; L/C;

    Nicotinamide mononucleotide (NMN) CAS Number 1094-61-7 Molecular Formula C11H15N2O8P Molecular Weight 334.22 EC Number 214-136-5 Package: Function: a cofactor for processes inside mitochondria, for sirtuins, and for PARP Application: a potential neuroprotective and anti-aging agent Tags: Delay aging.

    Nicotinamide mononucleotide ("NMN" and "β-NMN") is a nucleotide derived from ribose and nicotinamide.Like nicotinamide riboside, NMN is a derivative of niacin, and humans have enzymes that can use NMN to generate nicotinamide adenine dinucleotide (NADH). Nicotinamide mononucleotide (NMN) is proved by Harvard scientists to reverse aging process and may be new alternatives to aging, type II diabetes, cancers, muscle wasting and inflammatory diseases within five to ten years.

    Properties

    IUPAC name: 3-Carbamoyl-1-[5-O-(hydroxyphosphinato)-β-D-ribofuranosyl]pyridinium
    Other names: Nicotinamide ribonucleoside 5'-phosphate; Nicotinamide D-ribonucleotide;β-Nicotinamide ribose monophosphate; Nicotinamide nucleotide

    CAS-No: 1094-61-7
    Mol. Formula: C11H15N2O8P
    Mol. Weight: 334.22

    Mechanism of action
    NMN increase the NAD+ level in the body.Then, all the modes of acts of NMN is to be the mechanism of NAD+. β-Nicotinamide mononucleotide is a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

     

    Application

    Aging

    NAD(+) levels were increased significantly both in muscle and liver by NMN

    NMN-supplementation can induce similar reversal of the glucose intolerance

    NMN intervention is likely to be increased catabolism of fats

    NMN-supplementation does mimic exercise

    DNA Damage

    NMN was able to repair the DNA in cells damaged by radiation.

    Neurological Injury

    NMN treatment protects against cICH-induced acute brain injury

    NMN treatment reduces brain cell death and oxidative stress

    Further research

    This has precipitated dozens of studies since that are focused on investigating

    NMN supplementation to treat cardiovascular disease, diabetes, obesity, life extension,

    cancer, Alzheimer’s disease, Parkinson’s disease, and many more.

     

    Product List

    Product Name

    Grade

    Purity

    Package

    Nicotinamide mononucleotide

    Food grade

    ≥85%

    100g/ 1Kg/ 5Kg

    ≥95%

    100g/ 1Kg/ 5Kg

    Reagent grade

    ≥95%

    5g/25g

    Standard

    ≥98%

    100mg

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