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Nanoactive CIE is a novel type of golden chamomile extract nanoliposomal preparation. Golden chamomile extract (CIE) has a wide range of pharmacological effects. Golden chamomile extract has antibacterial, antiviral, anti-inflammatory, anti-allergic, antioxidant, protection against radiation damage and strengthens the skin protective barrier. The nanoactive substance of chamomile extract with a particle size of less than 30nm developed by the nano-delivery system (NDS) completely solves the solubility problem of chamomile essential oil, allowing it to be stably encapsulated in the nanocarrier, which can greatly increase the absorption efficiency and bioavailability. Nano Golden Chamomile Extract (Nanoactive CIE) has good efficacy and safety in the treatment of neonatal diaper dermatitis, lactating cracked nipples, sensitive skin, hormone-dependent skin (hormone face), and improving the sensitivity and elasticity of nipples and areolar areas of non-lactating women's breasts.