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Phenylethylresorcinol is a highly effective new skin whitening agent derived from silver pine, which has a super potential whitening effect: in vitro experiments have also proved that it is dozens or even hundreds of times stronger than VC, and its whitening ability has been clinically confirmed, which is comparable to the whitening ability of hydroquinone. After more than 10 years of continuous understanding of the nature and safety of these raw materials, it is gradually being licensed by various countries and gradually used in cosmetics, which is an emerging high-efficiency natural active substance. Phenethylresorcinol is insoluble in water, and is easy to be oxidized and easy to change color and other shortcomings limit its application in cosmetics, the use of nano delivery system (NDS) to develop a nanoactive substance with a particle size of less than 30nm, the phenylethylresorcinol is stably wrapped in the nanocarrier, which can greatly increase the absorption efficiency and bioavailability, overcome the original defects and maintain the advantages, and the application is more convenient and widespread.