Monoammonium Glycyrrhizinate, MAG

CERTIFICATION OF ANALYSIS

Product Name

MONOAMMONIUM GLYCYRRHIZINATE

ITEM

SPECIFICATION 

RESULT

CHARACTERS  

Appearance

White or yellowish-white, hygroscopic powder 

Complies

Solubility 

complies with the CRS 

Complies

IDENTIFICATION

Infrared spectrum

Corresponding to Reference Spectrum 

Complies

Alkaline reaction

complies with the CRS 

Complies

TEST  

Appearance of solution

Clear and not more intensely coloured than reference solution BY7 

Complies

Specific optical rotation

From +49.0 to +54.0 

+50.5

Related substances

18α-glycyrrhizic acid

NMT 10.0% 

8.9%

Impurity A

NMT 5.0% 

4.7%

Any other impurity

NMT 2.0% 

1.6%

Sum or other impurities

NMT7.0 % 

6.1%

Heavy Metals

NMT20ppm 

NMT20ppm

Water 

NMT6.0% 

3.6%

Sulphated ash

NMT0.2% 

0.01%

Residual ethanol 

NMT0.5%

0.2%

ASSAY

Ammonium Glycyrrhizate

From 98.0% to 102.0%(anhydrous substance) 

99.6%

Conclusion             Complies the lastest European Pharmacopoeia Standard