MINOCYCLINE HCl

Antibiotic from the tetracycline group. As a result of its longer half-life, it achieves plasma activities 2-4 times greater than its congeners (150 mg of minocycline demonstrated about 6 times greater activity than 250 mg of tetracycline within 24-48 h). It is mainly used in the treatment of acne and rosacea, since the single dose of 100 mg / day of this drug leads to a much greater therapeutic adherence than the four daily doses required with tetracycline and oxytetracycline. While its antibiotic spectrum has been shown to be much higher than that of the other members, including activity against Neisseria meningitidis, its prophylactic use has not been authorized due to its adverse effects (dizziness and vertigo). It can be used to treat Acinetobacter infections, resistant to multiple drugs. The other uses of Minocycline are shared with the other members of the Tetracyclines group.