Levodopa

Category:Active Pharmaceutical Ingredients > Biochemical Ingredients > Other Biochemical Ingredients
Product Name:Levodopa
CAS No.:59-92-7
Standard:ChP, USP, EP
Price(USD):Negotiable
Company:Han Traceability(Shaanxi) Biological Technology Co.,Ltd

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: xi’an , shaanxi,China

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe

  • Monthly Production Capacity: 500 kg

    Contract Manufacturing: CRO

    Packaging Information: As your requirements

  • Delivery Lead Time: 2-5days

    Sample Provided: yes

    Payment Terms: T/T

    Common Name:  Levodopa

    CAS Number:  59-92-7 

    Molecular Formula:  C9H11NO4 

    Molecular Weight:     197.188  

    L-DOPA is a natural form of DOPA used in the treatment of Parkinson's disease. L-DOPA is the precursor of dopamine and product of tyrosine hydroxylase.Target: Dopamine ReceptorL-DOPA (L-3,4-dihydroxyphenylalanine) is a chemical that is made and used as part of the normal biology of humans, some animals and plants. Some animals and humans make it via biosynthesis from the amino acid L-tyrosine. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine collectively known as catecholamines. L-DOPA can be manufactured and in its pure form is sold as apsychoactive drug with the INN levodopa; trade names include Sinemet, Parcopa, Atamet, Stalevo, Madopar, Prolopa, etc. As a drug it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia.L-DOPA crosses the protective blood-brain barrier, whereas dopamine itself cannot. Thus, L-DOPA is used to increase dopamine concentrations in the treatment of Parkinson's disease and dopamine-responsive dystonia. This treatment was made practical and proven clinically by George Cotzias and his coworkers, for which they won the 1969 Lasker Prize. In addition, L-DOPA, co-administered with a peripheral DDCI, has been investigated as a potential treatment for restless leg syndrome. However, studieshave demonstrated "no clear picture of reduced symptoms".

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