Leuprorelin

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:Leuprorelin
CAS No.:53714-56-0
Standard:ChP, USP, EP
Price(USD):Negotiable
Company:HYBIO PHARMACEUTICAL CO., LTD.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Wuhan, China

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East

  • Sample Provided: no

    Payment Terms: T/T

    Indications:

    • Advanced prostate cancer
    • Endometriosis
    • Central precocious puberty
    • Uterine fibroids
    • Some cases of infertility

    Mechanism of Action: Leuprorelin acts as an agonist at pituitary GnRH receptors. With continuous administration, it initially stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). However, with chronic use, it suppresses these hormones, leading to decreased testosterone in males and decreased estrogen in females.

    Pharmacokinetics:

    • Absorption: Depends on the formulation. Long-acting forms are developed to slowly release the drug.
    • Distribution: Distributed widely in the body.
    • Metabolism: Minimal metabolism, with the majority of the drug remaining intact.
    • Excretion: Excreted primarily through the kidneys.

    Form: Leuprorelin API is usually available as a white to off-white powder.

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