L-Selenomethionine

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:L-Selenomethionine
CAS No.:3211-76-5
Standard:In-house Standards
Price(USD):0.00
Company:Wuxi Accobio Biotech Inc

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: jiangsuwuxi

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Sample Provided: no

    • Product Name: L-Selenomethionine
      Synonyms: (S)-(+)-2-Amino-4-(methylseleno)butanoic acid
      Specification: 99%
      Appearance: White to off-white powder
      CAS No.: 3211-76-5
      Package: For minimal order: 1KG/Aluminium foil bag, 5 bags in a carton . For large quantity: 25KG/Fiber Drum in net weight; 28KG/Fiber Drum in gross weight (Can be customized)

       

      Products Description:


      The L-isomer of selenomethionine, known as Se-met and Sem, is a common natural food source of selenium. In vivo, selenomethionine is randomly incorporated instead of methionine and is readily oxidized. Its antioxidant activity arises from its ability to deplete reactive species. Selenium and sulfur are chalcogen elements that share many chemical properties and the substitution of methionine to selenomethionine may have no effect on protein structure and function. However, the incorporation of selenomethionine into tissue proteins and keratin in horses causes alkali disease. Alkali disease is characterized by emaciation, loss of hair, deformation and shedding of hooves, loss of vitality and erosion of the joints of long bones.

      Incorporation of selenomethionine into proteins in place of methionine aids the structure elucidation of proteins by X-ray crystallography using multi-wavelength anomalous diffraction (MAD). The incorporation of heavy atoms such as selenium helps solving the phase problem in X-ray crystallography.

      It has been suggested that selenomethionine, which is an organic form of selenium, is easier for the human body to absorb than selenite, which is an inorganic form. It was determined in a clinical trial that selenomethionine is absorbed 19% better than selenite.

     

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