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After absorption in gastrointestinal tract, the drug metabolize slowly in vivo, then gradually hydrolyze into nicotinic acid and inositol and plays role through the two products. It can ease and persistently relax peripheral vascular, improve the abnormal lipid metabolism, dissolve fibrin protein, thrombolytic and anticoagulant. It can be adjunctive therapy of hyperlipoprotememia, coronary heart disease and various peripheral vascular spasm (such as arteriosclerosis obliterans, Raynaud's disease, migraine etc.).
【Quality standard】：
ITEM
Standard
Result
Appearance:
White or White-like powder
White powder
Identify:
A B C conformed
Pass
Clear:
< BY6
Pass
Heavy Metal:
< 10ppm
Pass
Content:
98.0-101.0% Art No. ALA0029A
98.0-101.0%
Loss on drying:
< 0.5%
0.18%
CL:
< 350ppm
< 100ppm
Free Nicotinate acid:
< 0.8ml/g
0.20ml/g
Relative substance:
Conformed
Pass
Sulfate Ash:
< 0.1%
0.02%
Acetone:
Conformed
Pass
Total Plate Count:
< 1000cfu/g
< 100/g
Molds:
< 100cfu/g
< 10/g
Yeast:
< 100/g
< 10/g
E-Coli:
Negative
Negative
Salmonella:
Negative
Negative
Package:25kg/ paper drum or based on customer requirement.
Application:
In Clinic it can be adjunctive therapy of hyperlipidemia, coronary heart disease, peripheral vascular disorders (such as arteriosclerosis obliterans, Raynaud's disease, frostbite, vascular migraine etc.) adjuvant therapy.
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Pharma Sources Insight June 2024: Globalization on the Go
