Hualan's Human Rabies Immunoglobulin

[Characters]

It is a clear, colorless or light yellow liquid. Opalescence may occur but without turbidity.

[Indications]

The product is indicated for passive immunization of persons with wounds bitten or scratched by rabid dogs or other animals carrying rabies virus.

[Strengths]

200 IU per container (2.0 ml): each container containing 200 IU of rabies antibody potency, filling quantity of 2.0 ml.

[Administration and Dosage]

Administration: After extensive debridement, inject hypo. 1/2 of the total dosage at the wound, and inject i.m. the rest 1/2 (at back muscles if the wound was in head). WHO recommendation: Inject as much the product as possible at the wound; dilute 2～3 folds of the product with saline for use if the product is not enough.

Dosage: 20IU/kg BW or at the direction of the physician; the product should be used up at one time. If the dosage required exceeds 10 ml, divided dosing is allowed within 1～2 days. Afterwards, proceed the injection of rabies vaccine, but at a different site of injection and with a different equipment from that of the immunoglobulin.

[Adverse Reactions]

Generally no adverse reactions occur after injection. Erythema and swelling or pain in the site of injection may appear in a few people. Normally no treatment is necessary, for it could be relieved spontaneously.