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Category:Intermediates > Pharmaceutical Intermediates
Product Name:Heparin Sodium
CAS No.:9041-08-1
Standard:USP, BP, EP, JP, In-house Standards
Company:Seebio Biotech (Shanghai) Co., Ltd.
Grade: Food Grade
Factory Location: China
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East
Monthly Production Capacity: NA
Packaging Information: NA
Delivery Lead Time: 10-30days
Sample Provided: yes
Payment Terms: TT; L/C;
AHM0037A Heparin Sodium medicine grade CAS Number 9041-08-1;101921-26- Package: Function: prevent blood clotting , reduce blood fat,improve the coronary circulation Application: It has a wide range of uses in medicine Tags: Enrich the blood Anti Virus Blood lipid Regulation.
Heparin sodium is the sodium salt of sulfated glycosaminoglycan, it is a mixture of different kinds of different molecular weight molecules, which can keep the activity of the composition to against different factor in blood clotting stage. It exists in mammals and usually be extracted from mammals of the intestinal mucosa or the right organization of the mammals which are feed by human.
Heparin has strong anticoagulant effect, it is the primary drug choice to prevent deep vein thrombosis and thrombus diseases , although it has more than 60 years of history in clinic, but until now there is no substitutes can completely replace it, so it is still the most important biochemical drugs of anti coagulation and anti thrombosis.
Raw material resource :Porcine intestinal mucosa
Inspection items |
Specification |
|
Property |
White or off white powder, with strong hygroscopicity |
|
Identification |
Prolong the clotting time of complex calcium citrate sheep plasma |
|
NMR spectroscopy: complies |
||
HPLC:complies |
||
Complies the determination of sodium |
||
Inspection |
Clarity and color |
Clear and the staining degree is not over 5 chroma level of the control solution |
pH |
5.5~8.0 |
|
Nucleotide impurity |
A260≤0.15 |
|
Protein |
≤0.5% |
|
Relative substance |
Complies |
|
N |
1.5%~2.5%(dry basis) |
|
Na |
9.5~12.5% (dry basis) |
|
Heavy metal |
≤30 ppm |
|
Loss on drying |
≤8.0% |
|
Bacterial endotoxin |
<0.01 IU each international units of heparin |
|
Valency |
≥180 international units/mg (dry basis) |
|
Microbial test |
Total number of bacteria |
≤103 /g |
Molds and yeast count |
≤102 /g |
|
Intestinal bacteria and gram negative bacteria |
Not detected |
|
Escherichia coli |
Not detected |
|
Staphylococcus aureus |
Not detected |
|
Salmonella |
Not detected |
Storage: it should be stored in sealed container.
Function:
Common Heparin is a mixture containing a variety of amino dextran glucoside, it can delay or prevent blood clotting in vitro and in vivo. Heparin can reduce blood fat, decrease LDL and VLDL, increase HDL, changes blood viscosity, protect vascular endothelial cells, prevent atherosclerosis, promote blood flow, improve the coronary circulation.
It has a wide range of uses in medicine, it can be used to treat viral hepatitis, acute myocardial infarction, it can increase the efficacy of hepatitis B if combined with RNA, it can assist to chemotherapy and prevent thrombosis, it also has effects on reducing blood fat and enhance the body's immune function.
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