Hedyotis diffusa Extract

Product Name: Hedyotis diffusa Extract
Latin Name: Saposhnikovia Divaricata(Turcz.)Schischk.
Part of the Plant Used: Whole Herb
Specifications: 4:1 to 20:1
Test Method: TLC
Appereance: Yellow brown fine powder
Extract Method: Water

What is Hedyotis diffusa Extract?
Hedyotis diffusa Willd (HDW) has long been used as an important component in several Chinese medicine formulae to clinically treat various types of cancer, including colorectal cancer (CRC). Previously, we reported that HDW inhibits CRC growth via the induction of cancer cell apoptosis and the inhibition of tumor angiogenesis. In the present study, to further elucidate the mechanism of HDW-mediated antitumor activity, we investigated the effect of HDW ethanol extract (EEHDW) on the proliferation of HT-29 human colon carcinoma cells. We found that EEHDW reduced HT-29 cell viability and survival in a dose- and time‑dependent manner. We also observed that EEHDW treatment blocked the cell cycle, preventing G1 to S progression, and reduced mRNA expression of pro-proliferative PCNA, Cyclin D1 and CDK4, but increased that of anti-proliferative p21. Our findings suggest that Hedyotis diffusa Willd may be an effective treatment for CRC via the suppression of cancer cell proliferation.

Where will  Hedyotis diffusa Extract used to?
1).It could be used for treatment of digestive tract and lymphosy- stem cancers. 
2).It was effective against acute lymphocyte, granuloyte, mononucleoyte and chronic granulocyte leukemia cancer cells. 
3).Anti-bacteria and Anti-inflammation effect.

Application of Hedyotis diffusa Extract:
1).As pharmaceutical raw materials
2).Health care products