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Main Sales Markets: orth America,Central/South America,Western Europe,Eastern Europe,Australasia,Eastern Europe,Australasia,Asia,Middle East,Africa
Sample Provided: no
Therapeutic indications
Adults (20 years and over)
· Relief of nausea and vomiting associated with migraine, cancer therapy (chemotherapy or
radiation), malignant disease, labour, infectious disease and uraemia
· Control of post-operative vomiting
· Assist in small bowel intubation
Metoclopramide is of little benefit for the prevention or treatment of motion sickness.
Young Adults and Children (over 1 year of age)
Metoclopramide should be restricted to the following conditions and only used as second line therapy,
when used to treat children and young adults under 20 years of age because of the risk of adverse
effects:
· Severe intractable vomiting of known cause
· Vomiting associated with radiation therapy or intolerance to cytotoxic drugs
· Assist in small bowel intubatio
Dose and method of administration
Total daily doses of metoclopramide should not normally exceed 0.5 mg/kg bodyweight with a
maximum of 30 mg daily. This should be less (if possible) in children and young adults, when given
by injection. Maximum recommended treatment duration is 5 days in all age groups.
Usual dosage is as follows and should be administered intramuscularly or by slow intravenous
injection over 1 to 2 minutes.
Adults: 20 years and over: Maximum of 10 mg three times a day.
Young Adults: Treatment of young adults should commence at the lower dosage, and used as second line therapy only.
15 - 19 years: 5 mg to 10 mg three times a day.
Children: Treatment of children should commence at the lower dosage, where stated, and used as second line therapy only.
5 - 14 years: 2.5 mg to 5 mg three times a day.
3 - 5 years: 2 mg two to three times a day.
1 - 3 years: 1 mg two to three times a day.
Audited Supplier
Pharma Sources Insight June 2024: Globalization on the Go
