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Email ：PharmaSources@imsinoexpo.com
Whatsapp ：+86-13621645194
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Middle East
Monthly Production Capacity: 500kg
Contract Manufacturing: CRO
Packaging Information: As your requirements
Delivery Lead Time: 7-10days
Sample Provided: yes
Payment Terms: T/T
Gentiopicroside is a natural secoiridoid glycoside from gentian species of medicinal plants . It has exhibited a variety of pharmacological activities including hepatoprotective, anti-inflammatory, antinociceptive and smooth muscle relaxing activities .
In one study, the effects of Gentiopicroside on BLM-induced pulmonary fibrosis were investigated in mice. The results demonstrated that administration of Gentiopicroside significantly decreased the contents of TNF-α and IL-1β in BALF of mice. HYP and TGF-β1 in lung tissues also decreased after Gentiopicroside treatment. The alveolar epithelial cells and TGF-β1 could be the main target cells and molecules of Gentiopicroside on BLM-induced PF. Gentiopicroside may also has the potential in combination with nintedanib or pirfenidone in treatment of PF to synergize the therapeutic effects and minimize the adverse effects, but this needs further investigation.
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Pharma Sources Insight June 2024: Globalization on the Go
