G418 Sulfate

Name: G418 Sulfate
Availability: g418-sulfate-90270.html

Category:Active Pharmaceutical Ingredients > Antibiotics > Aminoglycoside
Product Name:G418 Sulfate
CAS No.:108321-42-2
Standard:In-house Standards
Price(USD):0.00
Company:Beijing Global Biologicals Co.Ltd

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Basic Info

Grade: Pharmaceutical Grade

Factory Location: shandong

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia,Middle East,Africa
Monthly Production Capacity: 100kgs

Contract Manufacturing: CRO,CMO

Packaging Information: as request
Sample Provided: yes

Payment Terms: T/T

Description

Geneticin (G418) Sulfate is an aminoglycoside antibiotic that has originally been derived from Micromonospora rhodoranga NRRL 5326. This compound has been shown to cause a bypass of nonsense mutations during translation. Experiments have shown that geneticin sulfate inhibits the incorporation of amino acids into protein and can destroy fibroblasts. Mechanistic studies suggest that this agent affects the 80S ribosome and inhibits the elongation cycle. Further studies report that geneticin sulfate is highly active against amoebae, protozoa, tapeworm, and pinworm exposed murine cells.

Usage

• Potency: ≥700 μg/mg

Technical Information

Appearance:	Powder
Physical State:	Solid
Solubility:	Soluble in water (50 mg/ml) and aqueous buffers.
Storage:	Store at 4° C
Boiling Point:	1012.1 °C at 760 mmHg (Predicted)

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