FiltraLinX® Lab-scale TFF System

FiltraLinX® Lab-scale TFF System is a modular system compatible with hollow fiber filters and cassettes of different specifications, covering the filtration areas from 0.005 m2 up to 0.5 m2.

This system is designed to be compact and practical, with a small circulation volume, making it suitable for high-concentration applications.

The system is equipped with a full set of components, including filtration tank, collection tank, OEM peristaltic pump, four element diaphragm pump, pressure sensor, electric pinch valve, multiport selector valve and automatic control system, to meet different experimental requirements. In the operating interface, you can adjust the flow rate to control tangential flow or adjust the pressure of retentate and permeate ends to achieve the TMP optimization. This enables the concentration, diafiltration, desalination, dealcoholization, and other operations for bioproducts such as antibodies, vaccines, blood products, gene therapy drugs, etc.

The system offers functions such as data recording, audit trial, permission management, and features high cost-effectiveness and compliance with relevant regulatory requirements, which makes it an ideal choice for laboratory research and development, pilot production, and small-batch GMP production.

• Ultrafiltration membrane filtration family with consistency and linearity, which can ensure the seamless transition of process scale-up or scale-down;

• Various specifications available: 0.005-0.5 m2 hollow fiber columns and cassettes;

• Equipped with electric pinch valve, pressure sensor, etc., realizing automatic adjustment of TMP;

• Fully functional with data recording, audit trial, permission management, etc.;

• Flexible connections, compatible with single-use storage and mixing bags used for the collection of product concentrates;

• Equipped with filtration tank, used for the temporary storage during product concentration, defiltration, harvest and clarification;

• Capable of automatically performing both the water flux test and the filter test;

• High compatibility. Compatible with hollow fiber columns and cassette filters;

• The frame is made of wear-resistant 304 stainless steel, while the product-contacting parts are made of 316L stainless steel;

• External surface polished to Ra ≤ 1.2 μm; product-contacting parts polished to Ra ≤ 0.4 μm;

• Parts in direct contact with the feed liquid are made of sanitary grade materials, such as 316L stainless steel, EPDM/PTFE/ TPE, etc. Certifications of the materials are available upon request;

• System pipeline withstands pressure up to 6 bar;

• Comes with a hollow fiber filter holder, fully equipped and ready for use upon arrival.

For more information please visit Bio-Link website.