FiltraLinX® Benchtop Semi-automatic TFF System

FiltraLinX® Semi-automatic TFF system applies a modular design, available with hollow fiber filters of different specifications,  covering the filtration areas from 0.017 m2  up to 1.1 m2. This system is designed compact and practical, with a small circulation volume, making it suitable for high-concentration  applications. The system is equipped with a full set of components, including filtration tank, collection tank, OEM peristaltic pump, four element  diaphragm pump, electric proportional control valve, temperature sensor, pressure sensor, ultrasonic flowmeter, and semi-automatic  control system, to meet different experimental requirements. The optimization of TMP point can be achieved through the operation  interface by adjusting the flow rate, tangential flow, and reflux and permeate pressure. This enables the concentration, diafiltration,  desalination, dealcoholization, and other operations for bioproducts such as antibodies, vaccines, blood products, gene therapy  drugs, etc. The system offers functions such as data recording, audit trial, permission management, and features high cost-effectiveness and compliance with relevant regulatory requirements, which makes it an ideal choice for laboratory research and development, pilot production, and small-batch GMP production.

• Hollow fiber filtration family with consistency and linearity, which can ensure the seamless transition of process scale-up or  scale-down;
• Various specifications available: 0.017-1.1 m2 hollow fiber filters;
• Equipped with the electric proportional control valve, pressure sensor, etc., realizing automatic adjustment of TMP;
• Fully functional with data recording, audit trial, permission management, etc.;
• Flexible connections, compatible with single-use storage and mixing bags used for the collection of product concentrations;
• Equipped with filtration tank, used for the temporary storage of the product concentration, defiltration, harvests and  clarifications;
• Capable of automatically performing both the water flux test and the filter test;
• With high compatibility, compatible with hollow fiber filters and cassettes membrane;
• The frame is made of wear-resistant 304 stainless steel, and the part in contact with the product is made of 316L stainless  steel;
• Polishing for the outer surface Ra ≤ 1.2 μm, polishing for the part in contact with the product Ra ≤ 0.4 μm;
• The part in direct contact with the feed liquid is made of sanitary grade materials, such as 316L stainless steel, EPDM/PTFE/ TPE, etc. Certifications of the materials are available upon request;
• System pipeline withstands pressure up to 6 bar;
• Full set of accessories including hollow fiber bracket, allowing for use upon arrival directly.

For more information, please visit Bio-Link website.