Fenbendazole

【name】Fenbendazole
【 CAS NO.】 43210-67-9 
【 description 】 white or kind of white powder, odourless, tasteless. This product is dissolved in dimethyl sulfoxide, slightly soluble in methanol, insoluble in water, dissolved in glacial acetic acid.
【pharmacological action】Finn benzene of azole for benzene and imidazoles deworming drugs, it not only have highly insecticide on gastrointestinal nematodes imagoes and larvae live sex, but also for web tail nematodes, piece trematode and tapeworm has good effect, have extremely strong kill eggs.
Sheep: the sheep blood spear nematodes, oster nematodes, wool round worms and worm cooper, thin neck nematodes, Yang mouth mouth nematodes, chabert nematodes, esophagus nematodes, MAO first nematodes, net tail nematodes imagoes and larvae are efficient. For extension moniezia, bayesian moniezia good drive effect. Of trematode need larger doses, such as 20 mg/kg, 5, the spear form double cavity trematode efficiency by 100%; A laparoscope, usually connected to a 15 mg/kg dose 6, is efficient for fasciola hepatica.
Bull: insecticide spectrum of cattle and sheep roughly similar to that of the trematode need higher doses, such as 7.5 ~ 10 mg/kg, 6, fasciola hepatica adult and plate of trematode worm tong before and after the cows are good results.
Horse: the horse vice worm, pointed tail nematodes imagoes and larvae, viviparous platts nematodes, ordinary round worms, no tooth round worms, ma round worms, small round worms have a good effect.
Pig: pig roundworm, red round worms, esophagus nematodes imagoes and larvae of the insect repellent effect is good. According to a laparoscope, usually connected to a 3 mg/kg (3, crown tail nematodes is also significant to kill.
Dogs, cats, dogs, internal and 25 mg/kg for dog hookworm, wool first worm, the worm effect is obvious. 50 mg/kg, 14, kill the transitional period of t. Canis larvae; Ed 3 can almost drive net tapeworm. Cat cat 3, by the treatment of roundworm, hookworm, tapeworms are efficient.
Wildlife: infected oster nematode, nematode, thin neck nematodes, cooper first nematodes, round worms, MAO MAO lung filarial deer internal and 5 mg/kg, 3 ~ 5, has a good effect, in addition to moniezia also to have certain effect. Of infected poultry worm, saw sting nematode, capillary nematodes and various prey, trematode to 25 mg/kg dose amount even served 3, almost all of the above insect body effectively.
【Limited】Poultry gastrointestinal and respiratory nematodes has fine effect of poultry. According to the quantity of 8 mg/kg/day, six days, to the chicken roundworm, capillary worms and tapeworms have high efficiency. For Turkey worm an effective dose of 350 mg/kg, but if to 45 mg/kg of feed concentration fed six days, even all net Turkey worm drive, sting nematode and closed capillary nematodes. The pheasant, partridge, grouse, goose and duck best insecticide solution is 60 mg/kg of feed concentration, 6 days. Natural infection closed capillary nematodes and pigeon pigeons worm, with 100 mg/kg mixed feeding, stay 3-4 days, efficient is close to 100%.
【 usage and dosage 】 oral a quantity per 1 kg weight, horses, cattle, sheep, pigs 5 ~ 7.5 mg; Poultry 10 ~ 50 mg; Dogs, cats, 25 to 50 mg.
【 notes 】 (1) application for a long time, can lead to drug-resistant strains.
(2) of this product in the rumen medications were given (including inside them) only abomasum dosing method than the insect repellent effect is good, can even enhance the resistant species expelling effect, may be the absorption rate is low, extend the drug is related to the effective concentration of insecticide in the host.
(3) the result of foreign has been proved that most of the experimental data, the continuous application of low dose, the insect repellent effect is better than that of a drug, suggest in case conditions allow, further tests to confirm and promotion.
(4) take medicine period of eight days, milk waste 3 days; 6 days, sheep milk disabled; The pig for five days.