Factory Supply Desmopressin acetate CAS16679-58-6 with Good Price
 

Basic Information

Desmopressin is a synthetic octapeptide, and an analogue of human hormone arginine vasopressin with antidiuretic and coagulant activities. Desmopressin binds to V2 receptors in renal collecting ducts which leads to exocytosis of von Willebrand factor (VWF) and tissue plasminogen activator (t-PA) from Weibel-Palade bodies, thereby increasing water resorption. This agent also increases nitric oxide (NO) production via activation of endothelial NO synthase, thereby induces afferent arteriolar vasodilation. Furthermore, desmopressin stimulates the release of factor VIII from endothelial cells mediated through V1a receptor, thereby promotes blood coagulation

APPLICATION&FUNCTION

This product is similar in structure to the natural hormone arginine vasopressin. Acting on V1 receptor, constricting blood vessels, acting on V2 receptor, producing antidiuretic effect, its antidiuretic effect is 400 times stronger than vasopressin, but its effect on smooth muscle is weak, and the effect of pressure is weak. After use, it can reduce urine excrement, increase urine osmotic pressure, and reduce plasma Chemicalbook osmotic pressure, thus reducing frequency and nocturia. This product is absorbed from the nasal mucosa, and the bioavailability is 10% ~ 20%. Most of them are destroyed in the gastrointestinal tract after oral administration, and the bioavailability is less than 0.5%, but large doses can produce therapeutic effects. If 0.1 ~ 0.2mg is taken orally, the antidiuretic effect can be maintained for 8 ~ 12 hours.

(1) Treatment of central diabetes insipidus. The drug can reduce urine discharge, reduce frequency of urination and reduce nocturia.

(2) Treatment of nocturnal enuresis (patients 5 years or older).

(3) To test the concentration function of kidney urine for differential diagnosis of renal function.

(4) for hemophilia and other Chemicalbook hemorrhagic diseases, this product can shorten the bleeding time and prevent bleeding. Can reduce the amount of intraoperative blood loss, reduce postoperative bleeding; In particular, combined with reasonably controlled intraoperative hypotension, intraoperative bleeding can be reduced from different mechanisms of action, and postoperative bleeding can be reduced, which can play a better role in blood protection. 

Other Peptide API&Intermediate

 Other Cosmetic Peptide Products

Why choose us :
The quality of our support is unmatched, We focus on the quality of our services. We're passionate about what we do. We welcome and act on your feedback. Proven track record. We provide a high level of support. We Guarantee Our Uptime, Support, and Services. Our Support Team is Friendly, Fast, and Knowledgeable. Our Customers Are Our Biggest Asset. Attention to Detail. AND OWN FACTORY OVER 10 YEARS~!!!!!!!!!!!!!!!!!!

 

About Us:

 ZhejiangHuajunPharmaceutical Co., Ltd., ( hereinafter calledHuajunpharma) a holding subsidiary of ZhejiangHuadiPharmaceutical Group Co., Ltd., was established in December 2015 with a registered capital of 50 millionyuan. In line with the tenet
of people-oriented, health promotion,HuajunPharmais mainly engaged in the research and development, production and sales ofnew products in the field of biopharmaceuticals. In November 2018,HuajunPharmawas recognized as a high-tech enterprise.

Huajunpharmafocuses on the production of synthetic peptide APIs,customized peptides, biochemical extracts and multi-componentbiochemical drugs. The representative products of synthetic peptides include:thymopentin, oxytocin,octreotide,Lanreotide,Leuprorelinetc. Biochemical extraction products include:Cerebroproteinhydrolysate, Ribonucleic acid,Thymosinpeptide,Chymotrypsin, Hepatocyte growth promoting factor (suckling pig liver extract), etc.


Huajunpharmahas Chinese GMP production line and R&D Center for synthetic polypeptide raw materials. It's also equipped withplant, equipment/facilities, storage area, air conditioning purification system and purified water preparation system which is suitable fordrug production. And there are trained and qualified production personnel, inspectors with technical ability to meet the productionrequirements.

Contact US

call us by 008613675847137

Email as at jayjie@hjyy.com

QQ: 1430571263