Exatecan

Name: Exatecan
Availability: exatecan-280148.html

Category:Intermediates > Pharmaceutical Intermediates
Product Name:Exatecan
CAS No.:171335-80-1
Standard:ChP
Price(USD):Negotiable
Company:Chemsphere Technology Inc.

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Basic Info

Grade: pharmaceutical grade

Factory Location: Taiwan

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Sample Provided: no

Payment Terms: T/T

Exatecan is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues.

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