Dimenhydrinate

Chemical Name

N-(2-Diphenylmethoxyethyl)-N,N-dimethylammonium 8-chlorotheophyllinate

CAS Number

523-87-5

Molecular Formula

C17H21NO.C7H7ClN4O2

Molecular Weight

469.97

Molecular Structure

Packing

25kg/drum

Capacity

5MT/M

Storage

Store in cool and dry place, keep away from strong light and heat

Application

It is used to prevent nausea and motion sickness, (emesis).

Items

Specification

Appearance

White crystalline powder or colorless crystals

Identification

Meets the requirements

Solubility

Slightly soluble in water, freely soluble in alcohol,sparingly soluble in ether

Melting Point

102.0 ~ 106.0℃

Appearanceof of Solution

Clear and colorless

pH

7.1 ~ 7.6

Theophyline and Substances Related to Diphenhydramine(TLC)

The theophylline≤0.5%

Any impurities ≤0.5%

Total Impurities

≤0.5%

Heavy Metals

≤20ppm

Loss on Drying

≤0.5%

Sulphated Ash

≤0.2%

Residual Solvents

2-Propanol ≤5000ppm

Toluene ≤890ppm

Assay

Diphenhydramine: 53.0 ~ 55.5%

8-Chlorotheophylline: 44.0 ~ 46.5%

Standard

BP/EP